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Anti-CFHR5 Monoclonal Antibody (2J764)
(Synonyms: FHR-5, FHR5, CFHR5D, CFHL5) Copy Product Info
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Synonyms: FHR-5, FHR5, CFHR5D, CFHL5
Catalog No. TMAC-00819 Copy Product Info
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Anti-CFHR5 Monoclonal Antibody (2J764) is a Mouse antibody targeting CFHR5. Anti-CFHR5 Monoclonal Antibody (2J764) can be used in WB,IHC,IF,FCM.
Anti-CFHR5 Monoclonal Antibody
(2J764)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $298 | 7-10 days | 7-10 days | |
| 100 µL | $428 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CFHR5 Monoclonal Antibody (2J764) is a Mouse antibody targeting CFHR5. Anti-CFHR5 Monoclonal Antibody (2J764) can be used in WB,IHC,IF,FCM. |
| Synonyms | FHR-5, FHR5, CFHR5D, CFHL5 |
| Ig Type | IgG2a |
| Clone | 2J764 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of CFHR5 on different cell lysate using anti-CFHR5 antibody at 1/1,000 dilution. Positive control: Lane1: HepG2, Lane2: K562, Lane3: L-02, Lane4: SK-Hep-1, Lane5: SMMC-7721, Lane6: NIH/3T3. 2. Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue using anti-CFHR5 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-CFHR5 antibody. Counter stained with hematoxylin. 4. ICC staining CFHR5 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of Hela cells with CFHR5 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).  , , , , |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CFHR5 |
| Gene ID | |
| Protein Name | Complement factor H-related protein 5 |
| Uniprot ID |
| Molecular Weight | Theoretical: 64.4 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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