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Anti-CDX2 Antibody (1N738)
😃Good
Catalog No. TMAC-00809
Alias Homeobox protein CDX-2, Homeobox protein CDX 2, CDX-3, CDX3, CDX2_HUMAN, CDX2, CDX 3, CDX 2, Caudal-type homeobox protein 2, caudal type homeobox transcription factor 2, Caudal type homeobox protein 2, caudal type homeobox 2, caudal type homeo box transcription factor 2, Caudal type homeo box 2
Anti-CDX2 Antibody (1N738) is a Rabbit antibody targeting CDX2. Anti-CDX2 Antibody (1N738) can be used in WB,ICC/IF,IHC,FCM.
Anti-CDX2 Antibody (1N738)
Anti-CDX2 Antibody (1N738)
😃Good
Catalog No. TMAC-00809Alias Homeobox protein CDX-2, Homeobox protein CDX 2, CDX-3, CDX3, CDX2_HUMAN, CDX2, CDX 3, CDX 2, Caudal-type homeobox protein 2, caudal type homeobox transcription factor 2, Caudal type homeobox protein 2, caudal type homeobox 2, caudal type homeo box transcription factor 2, Caudal type homeo box 2
Anti-CDX2 Antibody (1N738) is a Rabbit antibody targeting CDX2. Anti-CDX2 Antibody (1N738) can be used in WB,ICC/IF,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-CDX2 Antibody (1N738) is a Rabbit antibody targeting CDX2. Anti-CDX2 Antibody (1N738) can be used in WB,ICC/IF,IHC,FCM. |
| Synonyms | Homeobox protein CDX-2, Homeobox protein CDX 2, CDX-3, CDX3, CDX2_HUMAN, CDX2, CDX 3, CDX 2, Caudal-type homeobox protein 2, caudal type homeobox transcription factor 2, Caudal type homeobox protein 2, caudal type homeobox 2, caudal type homeo box transcription factor 2, Caudal type homeo box 2 |
| Ig Type | IgG |
| Reactivity | Human,Rat,Rabbit |
| Verified Activity | 1. Western blot analysis of CDX2 on AGS cells lysates using anti-CDX2 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-CDX2 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded rat large intestine tissue using anti-CDX2 antibody. Counter stained with hematoxylin. 4. ICC staining CDX2 in LOVO cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining CDX2 in AGS cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. Flow cytometric analysis of Hela cells with CDX2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The members of the murine Cdx family (Cdx1, Cdx2, and Cdx4) are members of the caudal-type homeobox family of genes, which are homologues of the Drosophila 'caudal' gene required for anterior-posterior regional identity. The intestine-specific transcription factors Cdx1 and Cdx2 are candidate genes for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. The relative expression of Cdx1 to Cdx2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Cdx1 and Cdx2 are expressed in the small intestine and colon of fetus and adult. A decrease in human Cdx1 and/or Cdx2 expression is associated with colorectal tumorigenesis. Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis, and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 34 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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