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Synonyms: TIP60, Protein lactyltransferase KAT5, Protein crotonyltransferase KAT5, Protein acetyltransferase KAT5, Protein 2-hydroxyisobutyryltransferase KAT5, Lysine acetyltransferase 5, KAT5, HTATIP, Histone acetyltransferase KAT5, Histone acetyltransferase HTATIP (HIV-1 Tat interactive protein), cPLA(2)-interacting protein, 60 kDa Tat-interactive protein (Tip60)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $428 | 7-10 days | 7-10 days |
| Description | Anti-KAT5 Antibody (3A803) is a Mouse antibody targeting KAT5. Anti-KAT5 Antibody (3A803) can be used in FCM,ICC,WB. |
| Synonyms | TIP60, Protein lactyltransferase KAT5, Protein crotonyltransferase KAT5, Protein acetyltransferase KAT5, Protein 2-hydroxyisobutyryltransferase KAT5, Lysine acetyltransferase 5, KAT5, HTATIP, Histone acetyltransferase KAT5, Histone acetyltransferase HTATIP (HIV-1 Tat interactive protein), cPLA(2)-interacting protein, 60 kDa Tat-interactive protein (Tip60) |
| Clone | 3A803 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 59 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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