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WDR5-0103 hydrochloride[890190-22-4(free base)]

🥰Excellent
Catalog No. T5140
Alias WD-Repeat Protein 5-0103

WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).

WDR5-0103 hydrochloride[890190-22-4(free base)]

WDR5-0103 hydrochloride[890190-22-4(free base)]

🥰Excellent
Purity: 99.66%
Catalog No. T5140Alias WD-Repeat Protein 5-0103
WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30In StockIn Stock
10 mg$51In StockIn Stock
25 mg$92In StockIn Stock
50 mg$159In StockIn Stock
100 mg$200In StockIn Stock
200 mg$292In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.66%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).
Targets&IC50
WDR5:450 nM (Kd)
SynonymsWD-Repeat Protein 5-0103
Chemical Properties
Molecular Weight419.9
FormulaC21H26ClN3O4
SmilesCl.COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cccc(OC)c2)c1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 18 mg/mL (42.87 mM), Sonication is recommended.
DMSO: 50 mg/mL (119.08 mM), Sonication is recommended.
H2O: Insoluble
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.3815 mL11.9076 mL23.8152 mL119.0760 mL
5 mM0.4763 mL2.3815 mL4.7630 mL23.8152 mL
10 mM0.2382 mL1.1908 mL2.3815 mL11.9076 mL
20 mM0.1191 mL0.5954 mL1.1908 mL5.9538 mL
DMSO
1mg5mg10mg50mg
50 mM0.0476 mL0.2382 mL0.4763 mL2.3815 mL
100 mM0.0238 mL0.1191 mL0.2382 mL1.1908 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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