Shopping Cart
Remove All
Your shopping cart is currently empty
UCB-J
Copy Product Info
🥰Excellent
Catalog No. T39069Cas No. 1604786-87-9
UCB-J is a radioligand for the synaptic vesicle protein 2A (SV2A), utilized in positron emission tomography (PET)[4].
UCB-J
Copy Product Info🥰Excellent
Catalog No. T39069Cas No. 1604786-87-9
UCB-J is a radioligand for the synaptic vesicle protein 2A (SV2A), utilized in positron emission tomography (PET)[4].
Product information is being updated, if you want to purchase, please click the bulk custom button.
Add to Quotation
Resource Download
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | UCB-J is a radioligand for the synaptic vesicle protein 2A (SV2A), utilized in positron emission tomography (PET)[4]. |
| In vivo | UCB-J demonstrates a significant unbound fraction (0.46 ± 0.02) and undergoes moderate metabolic rates in plasma, with 39% ± 5% and 24% ± 3% of the parent compound remaining after 30 and 90 minutes, respectively[3]. This compound also exhibits substantial uptake and rapid kinetics within the monkey brain[3]. Notably, pretreatment of an animal with UCB-J (150 μg/kg, iv) results in a reduction of the whole brain Standard Uptake Value (SUV) to levels comparable to those of the centrum semiovale, thereby highlighting [18F]7's in vivo binding specificity towards SV2A[4]. |
| Molecular Weight | 320.315 |
| Formula | C17H15F3N2O |
| Cas No. | 1604786-87-9 |
| Smiles | Cc1cnccc1CN1CC(CC1=O)c1cc(F)c(F)c(F)c1 |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy UCB-J | purchase UCB-J | UCB-J cost | order UCB-J | UCB-J chemical structure | UCB-J in vivo | UCB-J formula | UCB-J molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.