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Anti-NKX3A Antibody (1T251) is a Mouse antibody targeting NKX3A. Anti-NKX3A Antibody (1T251) can be used in WB,IHC,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $427 | 7-10 days |
Description | Anti-NKX3A Antibody (1T251) is a Mouse antibody targeting NKX3A. Anti-NKX3A Antibody (1T251) can be used in WB,IHC,FCM. |
Synonyms | NKX31_HUMAN, Nkx3-1, Nkx3.1, mouse, homolog of, NKX3.1, NKX3 1, NKX3, NKX 3A, Nkx 3.1, NKX 3, NK3 transcription factor related locus 1, NK3 transcription factor homolog A, NK3 homeobox 1, NK homeobox, family 3, member A, NK homeobox family 3 A, NK homeobox (Drosophila) family 3 A, Homeobox protein Nkx-3.1, Homeobox protein Nkx3.1, Homeobox protein Nkx 3.1, Homeobox protein NK-3 homolog A, BAPX2, BAPX 2 |
Clone | 1T251 |
Reactivity | Human |
Application | |
Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; FCM: 1:100-200 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
Research Background | The homeobox gene Nkx-3.1 is the human homolog of Drosophila bagpipe, which, in conjunction with tinman, determines cell fate in the dorsal mesoderm. In mammalian species, Nkx-3.1 is predominantly expressed in prostate, and it regulates prostate development in response to sonic hedgehog (Shh) signaling by exerting growth-suppressive and differentiating effects on prostatic epithelium. Nkx-3.1 is also expressed at lower levels in other tissues, including the heart and gut, in a Shh independent manner, where it plays a role in regulating proliferation of glandular epithelium and in the formation of ducts in prostate and minor salivary glands. Nkx-3.1 preferentially binds the TAAGTA sequence, which has not been reported for any other NK class homeoprotein. The human Nkx-3.1 gene is located on chromosome 8q21, which frequently undergoes a loss of heterozygosity, and although Nkx-3.1 is not a tumor suppressor gene, it may be a useful marker for benign and malignant prostate epithelium. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 26 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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