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Anti-UQCRC2 Antibody (7Z907)
(Synonyms: UQCRC 2, Ubiquinol-cytochrome-c reductase complex core protein 2, Cytochrome b-c1 complex subunit 2, Core protein II, Complex III subunit 2) Copy Product Info
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Synonyms: UQCRC 2, Ubiquinol-cytochrome-c reductase complex core protein 2, Cytochrome b-c1 complex subunit 2, Core protein II, Complex III subunit 2
Catalog No. TMAH-01235 Copy Product Info
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Anti-UQCRC2 Antibody (7Z907) is an antibody targeting UQCRC2. Anti-UQCRC2 Antibody (7Z907) can be used in ELISA,IHC,WB.
Anti-UQCRC2 Antibody
(7Z907)
(7Z907)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-UQCRC2 Antibody (7Z907) is an antibody targeting UQCRC2. Anti-UQCRC2 Antibody (7Z907) can be used in ELISA,IHC,WB. |
| Synonyms | UQCRC 2, Ubiquinol-cytochrome-c reductase complex core protein 2, Cytochrome b-c1 complex subunit 2, Core protein II, Complex III subunit 2 |
| Ig Type | Rabbit IgG |
| Clone | 7Z907 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. The 2 core subunits UQCRC1/QCR1 and UQCRC2/QCR2 are homologous to the 2 mitochondrial-processing peptidase (MPP) subunits beta-MPP and alpha-MPP respectively, and they seem to have preserved their MPP processing properties. May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS)/subunit 9 when incorporated into complex III (Probable). |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human UQCRC2 |
| Antigen Species | Human |
| Gene Name | UQCRC2 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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