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Anti-TRAF2 Antibody (6Y765)

(Synonyms: Tumor necrosis factor type 2 receptor-associated protein 3, TRAP3, TRAF 2, TNF receptor-associated factor 2, RING-type E3 ubiquitin transferase TRAF2, EC 2.3.2.27, E3 ubiquitin-protein ligase TRAF2) Copy Product Info
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Synonyms: Tumor necrosis factor type 2 receptor-associated protein 3, TRAP3, TRAF 2, TNF receptor-associated factor 2, RING-type E3 ubiquitin transferase TRAF2, EC 2.3.2.27, E3 ubiquitin-protein ligase TRAF2

Catalog No. TMAH-01212 Copy Product Info
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Anti-TRAF2 Antibody (6Y765) is an antibody targeting TRAF2. Anti-TRAF2 Antibody (6Y765) can be used in ELISA,FCM,IHC,IP,WB.
Anti-TRAF2 Antibody
(6Y765)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TRAF2 Antibody (6Y765) is an antibody targeting TRAF2. Anti-TRAF2 Antibody (6Y765) can be used in ELISA,FCM,IHC,IP,WB.
SynonymsTumor necrosis factor type 2 receptor-associated protein 3, TRAP3, TRAF 2, TNF receptor-associated factor 2, RING-type E3 ubiquitin transferase TRAF2, EC 2.3.2.27, E3 ubiquitin-protein ligase TRAF2
Ig Type
Rabbit IgG
Clone
6Y765
Reactivity
Human
Application
Recommended Dose
WB:1:500-1:5000; IHC:1:50-1:200; FCM:1:20-1:200; IP:1:200-1:1000.
Antibody Type
Monoclonal
Subcellular LocalizationCytoplasm.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundRegulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation; this does not depend on the TRAF2 RING-type zinc finger domain. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. In complex with BIRC2 or BIRC3, promotes ubiquitination of IKBKE.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human TRAF2
Antigen Species
Human
Gene Name
TRAF2
Gene ID
Uniprot ID
Biology Area
Cancer, Cardiovascular, Cell biology, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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