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DSSeb Crosslinker

Name: DSSeb Crosslinker
Brand: TargetMol
SKU: T19944
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T19944Cas No. 23024-29-5

Alias Sebacic acid bis N-succinimidyl ester, DSSeb, Disuccinimidyl sebacate

DSSeb Crosslinker (Disuccinimidyl sebacate) is a dual N-hydroxyethyl ketone ester and cell-membrane-permeable amine-reactive crosslinker, suitable for protein crosslinking and investigating protein-protein interactions.

DSSeb Crosslinker

🥰Excellent

Catalog No. T19944Alias Sebacic acid bis N-succinimidyl ester, DSSeb, Disuccinimidyl sebacateCas No. 23024-29-5

Pack Size	Price	Availability	Quantity
200 mg	$29	In Stock

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Product Introduction

Bioactivity

Description	DSSeb Crosslinker (Disuccinimidyl sebacate) is a dual N-hydroxyethyl ketone ester and cell-membrane-permeable amine-reactive crosslinker, suitable for protein crosslinking and investigating protein-protein interactions.
Synonyms	Sebacic acid bis N-succinimidyl ester, DSSeb, Disuccinimidyl sebacate

Chemical Properties

Molecular Weight	396.39
Formula	C₁₈H₂₄N₂O₈
Cas No.	23024-29-5
Smiles	O=C(ON1C(=O)CCC1=O)CCCCCCCCC(=O)ON2C(=O)CCC2=O
Relative Density.	1.31g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (100.91 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5228 mL	12.6138 mL	25.2277 mL	126.1384 mL
5 mM	0.5046 mL	2.5228 mL	5.0455 mL	25.2277 mL
10 mM	0.2523 mL	1.2614 mL	2.5228 mL	12.6138 mL
20 mM	0.1261 mL	0.6307 mL	1.2614 mL	6.3069 mL
50 mM	0.0505 mL	0.2523 mL	0.5046 mL	2.5228 mL
100 mM	0.0252 mL	0.1261 mL	0.2523 mL	1.2614 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DSSeb Cross-linkerDSSeb CrosslinkerDSSeb Cross linker