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Synonyms:
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $257 | 7-10 days | 7-10 days | |
| 100 μL | $379 | 7-10 days | 7-10 days |
| Description | Anti-LGR6 Antibody (9H672) is an antibody targeting LGR6. Anti-LGR6 Antibody (9H672) can be used in ELISA,FCM,IF,IHC. |
| Ig Type | Rabbit IgG |
| Clone | 9H672 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC:1:50-1:200; IF:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human LGR6 |
| Antigen Species | Human |
| Gene Name | LGR6 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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