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Anti-IFNAR1 Antibody (6J318) is a Mouse antibody targeting IFNAR1. Anti-IFNAR1 Antibody (6J318) can be used in WB,IP,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $428 | 7-10 days |
Description | Anti-IFNAR1 Antibody (6J318) is a Mouse antibody targeting IFNAR1. Anti-IFNAR1 Antibody (6J318) can be used in WB,IP,FCM. |
Reactivity | Mouse |
Application | |
Recommended Dose | WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate); FCM: 1 μg per 1 x 106 cells |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | The type I interferons (IFNs), ? and ∫, are a group of structurally and functionally related proteins that are induced by either viruses or double stranded RNA and defined by their ability to confer an antiviral state in cells. The ? and ∫ IFNs appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN?) binds to a distinct receptor. The latter protein, IFN-?R, is only weakly responsive to type I interferons in contrast to IFN-?/∫R, which binds to and responds effectively to IFN-∫ and to several of the IFN-? subtypes. Moreover, IFN-?/∫R is physically associated with the cytoplasmic tyrosine kinase JAK1 and thus, in addition to ligand binding, appears to be functionally involved in signal transduction. IFN-?R1 is a receptor for IFN-?/∫ and is present as the full chain (IFN-?R1a) and as a splice-variant (IFN-?R1). The IFN-? receptor complex consists of an alpha subunit (IFN-?R?) and a beta subunit that is 332 amino acids in length (mouse) and 337 amino acids in length (human). |
Conjucates | Unconjugated |
Immunogen | The extracellular domain of IFN-αR1 of mouse origin |
Antigen Species | mouse |
Uniprot ID |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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