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Naringenin triacetate

🥰Excellent
Catalog No. TN1973Cas No. 3682-04-0

Naringenin Triacetate is a derivative of the flavonoid Naringenin with improved lipid solubility and bioavailability, and good binding affinity for the Nac binding site of the structural domain of the BRD4 BET family protein BD1 (first bromodomain).

Naringenin triacetate
Other Forms of Naringenin triacetate:

Naringenin triacetate

🥰Excellent
Purity: 99.90%
Catalog No. TN1973Cas No. 3682-04-0
Naringenin Triacetate is a derivative of the flavonoid Naringenin with improved lipid solubility and bioavailability, and good binding affinity for the Nac binding site of the structural domain of the BRD4 BET family protein BD1 (first bromodomain).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$45-In Stock
5 mg$107-In Stock
10 mg$172-In Stock
25 mg$288-In Stock
50 mg$432-In Stock
100 mg$626-In Stock
200 mg$883-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.90%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Naringenin Triacetate is a derivative of the flavonoid Naringenin with improved lipid solubility and bioavailability, and good binding affinity for the Nac binding site of the structural domain of the BRD4 BET family protein BD1 (first bromodomain).
Chemical Properties
Molecular Weight398.36
FormulaC21H18O8
Cas No.3682-04-0
SmilesCC(=O)Oc1ccc(cc1)[C@@H]1CC(=O)c2c(OC(C)=O)cc(OC(C)=O)cc2O1
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from direct sunlight | store at 4°C | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (200.82 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (8.28 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5103 mL12.5515 mL25.1029 mL125.5146 mL
5 mM0.5021 mL2.5103 mL5.0206 mL25.1029 mL
10 mM0.2510 mL1.2551 mL2.5103 mL12.5515 mL
20 mM0.1255 mL0.6276 mL1.2551 mL6.2757 mL
50 mM0.0502 mL0.2510 mL0.5021 mL2.5103 mL
100 mM0.0251 mL0.1255 mL0.2510 mL1.2551 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Naringenin triacetateNaringenin
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