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Anti-NBN Antibody (9Z721)
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Catalog No. TMAC-03044
Alias p95 protein of the MRE11/RAD50 complex, p95, Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome 1, Nijmegen breakage syndrome, Nibrin, nibrin, NBS1, NBS 1, NBS, MGC87362, FLJ10155, Cell cycle regulatory protein p95, ATV, AT V2, AT V1
Anti-NBN Antibody (9Z721) is a Rabbit antibody targeting NBN. Anti-NBN Antibody (9Z721) can be used in WB,ICC/IF,IP,FCM,IHC,ChIP.
Anti-NBN Antibody (9Z721)
Anti-NBN Antibody (9Z721)
😃Good
Catalog No. TMAC-03044Alias p95 protein of the MRE11/RAD50 complex, p95, Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome 1, Nijmegen breakage syndrome, Nibrin, nibrin, NBS1, NBS 1, NBS, MGC87362, FLJ10155, Cell cycle regulatory protein p95, ATV, AT V2, AT V1
Anti-NBN Antibody (9Z721) is a Rabbit antibody targeting NBN. Anti-NBN Antibody (9Z721) can be used in WB,ICC/IF,IP,FCM,IHC,ChIP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-NBN Antibody (9Z721) is a Rabbit antibody targeting NBN. Anti-NBN Antibody (9Z721) can be used in WB,ICC/IF,IP,FCM,IHC,ChIP. |
| Synonyms | p95 protein of the MRE11/RAD50 complex, p95, Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome 1, Nijmegen breakage syndrome, Nibrin, nibrin, NBS1, NBS 1, NBS, MGC87362, FLJ10155, Cell cycle regulatory protein p95, ATV, AT V2, AT V1 |
| Ig Type | IgG |
| Clone | 9Z721 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Nibrin on human lung lysates using anti-p95 NBS1 antibody at 1/1,000 dilution. 2. ICC staining p95 NBS1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining p95 NBS1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of Hela cells with p95 NBS1antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000; IHC: 1:50; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | DNA repair proteins are necessary for the maintenance of chromosome integrity and are involved in the elimination of premutagenic lesions from DNA. The DNA repair proteins Rad51 and Rad52 are key components of the double-strand-break repair (DSBR) pathway. Rad51 is essential for mitotic and meiotic recombination, and its mutation in yeast and mammalian cells results in chromosome loss. Overexpression of Rad52 confers resistance to ionizing radiation and induces homologous intrachromosomal recombination. Rad52 is thought to be involved in an early stage of Rad51-mediated recombination. Additional proteins involved in the pathway include Dmc1 and nibrin. Dmc1 is specifically involved in meiotic recombination. Nibrin, which complexes with Mre11 and Rad50, is absent in Nijemegen breakage syndrome (NBS) patients. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 95 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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