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Anti-MCM5 Antibody (9C193)
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Catalog No. TMAC-02500
Alias P1-CDC46, P1 CDC46, Minichromosome maintenance deficient protein 5, Minichromosome maintenance deficient 5, Minichromosome maintenance deficient (S. cerevisiae) 5, Minichromosome maintenance complex component 5, MGC5315, MCM5_HUMAN, MCM5, MCM 5, DNA replication licensing factor MCM5, DNA replication licensing factor MCM 5, DNA replication licensing factor, Cell division cycle 46, CDC46 homolog, CDC46, CDC 46
Anti-MCM5 Antibody (9C193) is a Rabbit antibody targeting MCM5. Anti-MCM5 Antibody (9C193) can be used in WB,IHC.
Anti-MCM5 Antibody (9C193)
Anti-MCM5 Antibody (9C193)
😃Good
Catalog No. TMAC-02500Alias P1-CDC46, P1 CDC46, Minichromosome maintenance deficient protein 5, Minichromosome maintenance deficient 5, Minichromosome maintenance deficient (S. cerevisiae) 5, Minichromosome maintenance complex component 5, MGC5315, MCM5_HUMAN, MCM5, MCM 5, DNA replication licensing factor MCM5, DNA replication licensing factor MCM 5, DNA replication licensing factor, Cell division cycle 46, CDC46 homolog, CDC46, CDC 46
Anti-MCM5 Antibody (9C193) is a Rabbit antibody targeting MCM5. Anti-MCM5 Antibody (9C193) can be used in WB,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-MCM5 Antibody (9C193) is a Rabbit antibody targeting MCM5. Anti-MCM5 Antibody (9C193) can be used in WB,IHC. |
| Synonyms | P1-CDC46, P1 CDC46, Minichromosome maintenance deficient protein 5, Minichromosome maintenance deficient 5, Minichromosome maintenance deficient (S. cerevisiae) 5, Minichromosome maintenance complex component 5, MGC5315, MCM5_HUMAN, MCM5, MCM 5, DNA replication licensing factor MCM5, DNA replication licensing factor MCM 5, DNA replication licensing factor, Cell division cycle 46, CDC46 homolog, CDC46, CDC 46 |
| Ig Type | IgG |
| Clone | 9C193 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of MCM5 on different lysates using anti-MCM5 antibody at 1/500 dilution. Positive control: Lane 1: Mouse thymus tissue, Lane 2: SiHa. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-MCM5 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-MCM5 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-MCM5 antibody. Counter stained with hematoxylin. |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1 to S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the postreplicative state of the cell. MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro. Cleavage of MCM3, which can be prevented by caspase inhibitors, results in the inactivation during apoptosis of the MCM complex, which is composed of, at least, MCM2?C6. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: within C terminal human MCM5 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 82 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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