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2-Hydroxybutyric acid

🥰Excellent
Catalog No. T4322Cas No. 600-15-7
Alias α-Hydroxybutyric acid

2-Hydroxybutyric acid (α-Hydroxybutyric acid) is a product of protein metabolism and serves as a biomarker for type 2 diabetes and pre-eclampsia.

2-Hydroxybutyric acid
Other Forms of 2-Hydroxybutyric acid:
Sodium 2-hydroxybutanoateT47385094-24-6
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2-Hydroxybutyric acid

🥰Excellent
Purity: 98.00%
Catalog No. T4322Alias α-Hydroxybutyric acidCas No. 600-15-7
2-Hydroxybutyric acid (α-Hydroxybutyric acid) is a product of protein metabolism and serves as a biomarker for type 2 diabetes and pre-eclampsia.
Pack SizePriceAvailabilityQuantity
50 mg$35In Stock
100 mg$53In Stock
500 mg$113In Stock
1 g$163In Stock
1 mL x 10 mM (in DMSO)$37In Stock
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Purity:98.00%
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Product Introduction

Bioactivity
Description
2-Hydroxybutyric acid (α-Hydroxybutyric acid) is a product of protein metabolism and serves as a biomarker for type 2 diabetes and pre-eclampsia.
In vitro
2-Hydroxybutyric acid (0-40 mM; 24-48 hours) can decrease AP-induced toxicity in AML12, BRL3A, and primary hepatocytes from mice[3].
In vivo
2-Hydroxybutyric acid（250 mg/kg；i.p. for 3 days）Prevented AP-induced liver injury in C57 mice[3].
Synonymsα-Hydroxybutyric acid
Chemical Properties
Molecular Weight104.1
FormulaC4H8O3
Cas No.600-15-7
SmilesCCC(O)C(O)=O
Relative Density.1.195 g/cm3
Storage & Solubility Information
Storagekeep away from moisture,store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (480.31 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (19.21 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM9.6061 mL48.0307 mL96.0615 mL480.3074 mL
5 mM1.9212 mL9.6061 mL19.2123 mL96.0615 mL
10 mM0.9606 mL4.8031 mL9.6061 mL48.0307 mL
20 mM0.4803 mL2.4015 mL4.8031 mL24.0154 mL
50 mM0.1921 mL0.9606 mL1.9212 mL9.6061 mL
100 mM0.0961 mL0.4803 mL0.9606 mL4.8031 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

EndogenousMetaboliteEndogenous MetaboliteCompound T-4322Compound T4322Compound T 4322
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