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Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensatory cirrhosis caused by non-alcoholic steatohepatitis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $222 | In Stock | In Stock | |
| 5 mg | $563 | In Stock | In Stock | |
| 10 mg | $913 | - | In Stock | |
| 25 mg | $1,370 | - | In Stock | |
| 50 mg | $1,850 | - | In Stock | |
| 100 mg | $2,490 | - | In Stock |
| Description | Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensatory cirrhosis caused by non-alcoholic steatohepatitis. |
| Synonyms | GS 6624, AB 0024 |
| Reactivity | Human |
| Verified Activity | Immobilized Human LOXL2 Protein (His) at 2 μg/mL (30 μL/well) can bind Simtuzumab. The EC50 is 38.57 ng/mL. ![]() |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | LOXL2 |
| Molecular Weight | 150.00 kDa |
| Cas No. | 1318075-13-6 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG4SP kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Size | Quantity | Unit Price | Amount | Operation |
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