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Simtuzumab (Synonyms: GS 6624, AB 0024)

Catalog No. T76700 Copy Product Info
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Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensatory cirrhosis caused by non-alcoholic steatohepatitis.

Simtuzumab

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Catalog No. T76700
Synonyms GS 6624, AB 0024

Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensatory cirrhosis caused by non-alcoholic steatohepatitis.

Simtuzumab
Cas No. 1318075-13-6
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$222In StockIn Stock
5 mg$563In StockIn Stock
10 mg$913-In Stock
25 mg$1,370-In Stock
50 mg$1,850-In Stock
100 mg$2,490-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensatory cirrhosis caused by non-alcoholic steatohepatitis.
SynonymsGS 6624, AB 0024
Reactivity
Human
Verified Activity
Immobilized Human LOXL2 Protein (His) at 2 μg/mL (30 μL/well) can bind Simtuzumab. The EC50 is 38.57 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetLOXL2
Chemical Properties
Molecular Weight150.00 kDa
Cas No.1318075-13-6
Antibody Information
IsotypeHuman IgG4SP kappa
Recommended Isotype Control
Storage & Solubility Information
Storage-20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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