Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TargetMol | Compound Library

Fluorochemical Library

Catalog No. L5100

Fluorine atoms have a unique combination of electronic and physical properties. As such, when incorporated into active pharmaceutical ingredients (APIs), fluorine atoms often influence their protein binding affinity and lipophilicity but not the shape of the resulting fluorochemicals. Fluorination can thus significantly impact the bioavailability or metabolic stability of drug substances. The pivotal role that the element fluorine plays in modulating the properties of bioactive molecules is reflected by the growth of its presence in approved drugs, as evidenced by the fact that between 15% to 20% of all medicines and agrochemicals on the market contain at least one fluorine atom in their structure. As of 2009, the FDA had approved >140 fluorine-containing drugs, such as fluorouracil, Miglitol, Gemcitabine, Sofosbuvir, atorvastatin, fluoxetine, ciprofloxacin, etc. The judicious introduction of fluorine into a molecule can productively influence conformation, pKa, intrinsic potency, membrane permeability, metabolic pathways, and pharmacokinetic properties. Nowadays, the application of specialty fluorochemicals in the pharmaceutical industry has been increasingly widespread. TargetMol's fluorochemical library has become an effective tool for developing new anticancer drugs, anesthetics, antidepressants, antifungals, antiviral drugs, antibiotics, cholesterol lowering agents, and anti-inflammatory agents. In addition, in agricultural uses, the addition of fluorine to many agricultural herbicides, pesticides, and fungicides improves the potency and therefore reduces the required application rate of these substances.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Resource Download
Library compound info
Excel
SDF
Contact us for more batch information

Catalog No. L5100

Fluorochemical Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
Inquiry & Custom

Top Publication Citing
Use of TargetMol Products

Cite scientific literature on TargetMol products

View More

Product Description Product Description

  • A unique collection of 2684 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Sci Citations

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
Inquiry & Custom

Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
5-HT Receptor
Antibacterial
VEGFR
EGFR
Antibiotic
Dehydrogenase
PI3K
Dopamine Receptor
DNA/RNA Synthesis
Raf
Sodium Channel
Antifungal
CDK
Potassium Channel
COX
FLT
p38 MAPK
PDGFR
HIV Protease
c-Met/HGFR
Parasite
TRP/TRPV Channel
GluR
c-Kit
Calcium Channel
PDE
Bcr-Abl
Glucocorticoid Receptor
Androgen Receptor
Src
JAK
Epigenetic Reader Domain
GPR
Prostaglandin Receptor
Histone Methyltransferase
HCV Protease
Adrenergic Receptor
GABA Receptor
AChR
PARP
Phospholipase
Aurora Kinase
SARS-CoV
FGFR
MEK
Nucleoside Antimetabolite/Analog
HER
CCR
mTOR
Topoisomerase
Cytochromes P450
PPAR
Gamma-secretase
MAPK
HBV
c-RET
TAM Receptor
Histamine Receptor
Trk receptor
HDAC
Microtubule Associated
ERK
iGluR
DUB
Antiviral
Proteasome
ROR
Estrogen/progestogen Receptor
Phosphatase
Tyrosine Kinases
Akt
Influenza Virus
S6 Kinase
Reductase
GSK-3
NMDAR
ALK
Casein Kinase
STAT
Kras
YAP
Virus Protease
Wnt/beta-catenin
Cysteine Protease
Caspase
IL Receptor
Ras
CFTR
Proton pump
Adenosine Receptor
Estrogen Receptor/ERR
PKC
ROCK
Glucagon Receptor
Guanylate cyclase
CXCR
Histone Acetyltransferase
IκB/IKK
NF-κB
PLK
HIF
Discoidin Domain Receptor (DDR)
Neurokinin receptor
FAK
S1P Receptor
Mdm2
LPL Receptor
CETP
Liver X Receptor
MAO
E1/E2/E3 Enzyme
Isocitrate Dehydrogenase (IDH)
DPP-4
Epoxide Hydrolase
Indoleamine 2,3-Dioxygenase (IDO)
TGF-beta/Smad
HSP
STING
Bcl-2 Family
TNF
Cannabinoid Receptor
HMG-CoA Reductase
Ferroptosis
BACE
Mitophagy
Rho
Serotonin Transporter
RIP kinase
P2X Receptor
ROS
Hedgehog/Smoothened
Lipoxygenase
transporter
Beta Amyloid
AMPK
Hydroxylase
ROS Kinase
Chloride channel
PERK
IDO
BTK
Opioid Receptor
FAAH
OX Receptor
Interleukin
Ephrin Receptor
Reverse Transcriptase
Carbonic Anhydrase
DNA-PK
P2Y Receptor
Lipase
Serine Protease
Aryl Hydrocarbon Receptor
GRK
DNA gyrase
Reactive Oxygen Species
Neuropeptide Y Receptor
Stearoyl-CoA Desaturase (SCD)
LRRK2
Nrf2
ATM/ATR
c-Fms
Syk
IRAK
HIF/HIF Prolyl-Hydroxylase
p53
ATPase
Transferase
CRM1
Tie-2
GTPase
c-Myc
GNRH Receptor
PKA
Pim
Glucokinase
CSF-1R
Mitochondrial Metabolism
Smo
Chk
Beta-Secretase
Acyltransferase
P-gp
TLR
PI4K
Sigma receptor
AhR
Kinesin
Monoamine Oxidase
Melanin-concentrating Hormone Receptor (MCHR)
NOS
Integrin
DYRK
Serine/threonin kinase
GlyT
Fatty Acid Synthase
PAK
HSV
MMP
IGF-1R
Norepinephrine
RSV
Retinoid Receptor
Endogenous Metabolite
PDK
DNA Methyltransferase
Antioxidant
NADPH
Leukotriene Receptor
Neurotensin Receptor
FXR
LIM Kinase
IAP
Myosin
IRE1
Drug Metabolite
DNA Alkylation
Somatostatin
SGLT
OXPHOS
PGE Synthase
Sirtuin
ASK
Methionine Adenosyltransferase (MAT)
GHSR
Complement System
NOD
Protease-activated Receptor
MicroRNA
Monocarboxylate transporter
RAR/RXR
MALT
ADC Cytotoxin
DprE1
Arrestin
IFNAR
Histone Demethylase
RAAS
JNK
Factor Xa
Galectin
CaSR
MRP
NAMPT
PYK2
Glutaminase
SIK
Annexin A
Phosphorylase
Antifection
Integrase
Vasopressin Receptor
ACK1
Xanthine Oxidase
cAMP
CaMK
Telomerase
MRGPR
Porcupine
CRFR
GPX
LPA Receptor
CGRP Receptor
SGK
Tyrosinase
NOD-like Receptor (NLR)
Thyroid hormone receptor(THR)
PROTACs
Adenylyl Cyclase
NPC1L1
DHFR
NEDD8
Amino Acids and Derivatives
Glutaminyl Cyclase
LTR
Na+/Ca2+ Exchanger
Glutathione Peroxidase
Progesterone Receptor
OCT
N-Acetylglucosaminyltransferase
Cholecystokinin Receptor
AAK1
VDAC
Hck
RANKL/RANK
FOXO1
Immunology/Inflammation related
UGT
MTH1
LDL
Monoamine Transporter
Anion Exchanger
Bombesin Receptor
Bradykinin Receptor
PTEN
KSP
DNA
ATP Citrate Lyase
BCRP
PSMA
OAT
MNK
Survivin
CD73
AIM2
GluCls
PAI-1
MELK
Acetyl-CoA Carboxylase
Protease
Aromatase
Melanocortin Receptor
KLF
Aquaporin
RXFP receptor
Anti-infection
BMI-1
Thrombin
Lysosomal Autophagy
MLK
PD-1/PD-L1
PKM
NO Synthase
Sodium-dependent phosphate transporter