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Anti-SOCS7 Antibody (7J279)
(Synonyms: Suppressor of cytokine signaling 7, SOCS-7, SOCS6, Nck-associated protein 4, Nck, NAP-4, NAP4, Ash and phospholipase C gamma-binding protein) Copy Product Info
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Synonyms: Suppressor of cytokine signaling 7, SOCS-7, SOCS6, Nck-associated protein 4, Nck, NAP-4, NAP4, Ash and phospholipase C gamma-binding protein
Catalog No. TMAH-01119 Copy Product Info
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Anti-SOCS7 Antibody (7J279) is an antibody targeting SOCS7. Anti-SOCS7 Antibody (7J279) can be used in ELISA,FCM,IHC.
Anti-SOCS7 Antibody
(7J279)
(7J279)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SOCS7 Antibody (7J279) is an antibody targeting SOCS7. Anti-SOCS7 Antibody (7J279) can be used in ELISA,FCM,IHC. |
| Synonyms | Suppressor of cytokine signaling 7, SOCS-7, SOCS6, Nck-associated protein 4, Nck, NAP-4, NAP4, Ash and phospholipase C gamma-binding protein |
| Ig Type | Rabbit IgG |
| Clone | 7J279 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Note=Mostly cytoplasmic, but shuttles between the cytoplasm and the nucleus. Rapidly relocalizes to the nucleus after UV irradiation. Cytoplasmic location depends upon SEPT7 presence. |
| Tissue Specificity | Expressed in brain and leukocytes. Also in fetal lung fibroblasts and fetal brain. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human SOCS7 |
| Antigen Species | Human |
| Gene Name | SOCS7 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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