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Anti-SATB1 Antibody (9Q281) (Synonyms: Special AT-rich sequence-binding protein 1, Special AT rich sequence bin...)
Catalog No. TMAC-03687 Copy Product Info
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Anti-SATB1 Antibody (9Q281) is a Rabbit antibody targeting SATB1. Anti-SATB1 Antibody (9Q281) can be used in FCM,ICC/IF,IHC,IP,WB.
Anti-SATB1 Antibody (9Q281)
Copy Product Info🥰Excellent
Catalog No. TMAC-03687
Synonyms Special AT-rich sequence-binding protein 1, Special AT rich sequence binding protein 1 (binds to nuclear matrix/scaffold associating DNA), Special AT rich sequence binding protein 1, SATB1_HUMAN, SATB homeobox 1, SATB 1, DNA-binding protein SATB1, DNA binding protein SATB1
Anti-SATB1 Antibody (9Q281) is a Rabbit antibody targeting SATB1. Anti-SATB1 Antibody (9Q281) can be used in FCM,ICC/IF,IHC,IP,WB.
Anti-SATB1 Antibody
(9Q281)
(9Q281)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-SATB1 Antibody (9Q281) is a Rabbit antibody targeting SATB1. Anti-SATB1 Antibody (9Q281) can be used in FCM,ICC/IF,IHC,IP,WB. |
| Synonyms | Special AT-rich sequence-binding protein 1, Special AT rich sequence binding protein 1 (binds to nuclear matrix/scaffold associating DNA), Special AT rich sequence binding protein 1, SATB1_HUMAN, SATB homeobox 1, SATB 1, DNA-binding protein SATB1, DNA binding protein SATB1 |
| Ig Type | IgG |
| Clone | 9Q281 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of SATB1 on human thymus lysates using anti-SATB1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat spleen tissue using anti-SATB1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse thymus tissue using anti-SATB1 antibody. Counter stained with hematoxylin. 4. Flow cytometric analysis of Jurkat cells with SATB1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.     |
| Application | |
| Recommended Dose | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The homeoproteins CCAAT displacement protein (CDP) and special AT-rich sequence binding protein 1 (SATB1) are transcriptional repressors of many cellular genes, and they participate in cell development and cell type differentiation. SATB1 is expressed primarily in thymocytes, and, like CDP, it also contains a distinct homeobox DNA-binding domain that is essential for DNA binding. SATB1 and CDP interact through these homeodomains and synergistically function as mediators of gene expression. SATB1 contains an additional domain that has a higher affinity for DNA and specifically facilitates the direct association between SATB1 and the nuclear matrix attachment regions (MARs) of DNA. MARs are specific DNA sequences that bind to the nuclear matrix and form the base of chromosomal loops that organize the chromosomes and regulate DNA transcription and replication within the nucleus. The association of SATB1 with the core unwinding element within the base-unpairing region of MARs requires both the MAR and homeobox binding domains of SATB1. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 100 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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