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Anti-CLOCK Antibody (3L638)
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Catalog No. TMAC-00896
Alias KIAA0334, hCLOCK, CLOCK_HUMAN, Clock protein, Clock homolog, Clock circadian regulator, CLOCK, Class E basic helix-loop-helix protein 8, Circadium Locomotor Output Cycles Kaput, Circadian Locomotor Output Cycles Kaput, Circadian locomoter output cycles protein kaput, Circadian locomoter output cycles kaput protein, bHLHe8
Anti-CLOCK Antibody (3L638) is a Rabbit antibody targeting CLOCK. Anti-CLOCK Antibody (3L638) can be used in WB,ICC/IF,IHC,FCM.
Anti-CLOCK Antibody (3L638)
Anti-CLOCK Antibody (3L638)
😃Good
Catalog No. TMAC-00896Alias KIAA0334, hCLOCK, CLOCK_HUMAN, Clock protein, Clock homolog, Clock circadian regulator, CLOCK, Class E basic helix-loop-helix protein 8, Circadium Locomotor Output Cycles Kaput, Circadian Locomotor Output Cycles Kaput, Circadian locomoter output cycles protein kaput, Circadian locomoter output cycles kaput protein, bHLHe8
Anti-CLOCK Antibody (3L638) is a Rabbit antibody targeting CLOCK. Anti-CLOCK Antibody (3L638) can be used in WB,ICC/IF,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-CLOCK Antibody (3L638) is a Rabbit antibody targeting CLOCK. Anti-CLOCK Antibody (3L638) can be used in WB,ICC/IF,IHC,FCM. |
| Synonyms | KIAA0334, hCLOCK, CLOCK_HUMAN, Clock protein, Clock homolog, Clock circadian regulator, CLOCK, Class E basic helix-loop-helix protein 8, Circadium Locomotor Output Cycles Kaput, Circadian Locomotor Output Cycles Kaput, Circadian locomoter output cycles protein kaput, Circadian locomoter output cycles kaput protein, bHLHe8 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of CLOCK on MCF-7 (1) and PC-12 (2) cell using anti-CLOCK antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-CLOCK antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded 2 colon tissue using anti-CLOCK antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-CLOCK antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CLOCK antibody. Counter stained with hematoxylin. 6. ICC staining CLOCK in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining CLOCK in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. Flow cytometric analysis of Hela cells with CLOCK antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Biological timepieces called circadian clocks are responsible for the regulation of hormonal rhythms, sleep cycles and other behaviors. The superchiasmatic nucleus (SCN), which is located in the brain, was the first mammalian circadian clock to be discovered. Clock, a member of the Basic-helix-loop-helix-psp (bHLH-PAS) family of transcription factors, has also been identified as having circadian function. Mutations within the clock gene have been shown to increase the length of the endogenous period and To contain a loss of rhythmicity of circadian oscillations. Clock contains a DNA-binding domain, a protein dimerization domain and a glutamine-rich C-terminal region, which indicates transactivation ability. It has been speculated that Clock may regulation circadian rhythmicity in combination with Other proteins such as Per. Per is also a PAS-domain containing protein that exhibits circadian function. Highest expression of Clock is seen in the hypothalamus and the eye. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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