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Anti-VDB Antibody (2T657)

(Synonyms: Vitamin D-binding protein, VDB, Group-specific component, Gc-globulin, Gc, DBP) Copy Product Info
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Synonyms: Vitamin D-binding protein, VDB, Group-specific component, Gc-globulin, Gc, DBP

Catalog No. TMAC-04264 Copy Product Info
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Anti-VDB Antibody (2T657) is a Rabbit antibody targeting VDB. Anti-VDB Antibody (2T657) can be used in FCM,ICC/IF,IHC,WB.
Anti-VDB Antibody
(2T657)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-VDB Antibody (2T657) is a Rabbit antibody targeting VDB. Anti-VDB Antibody (2T657) can be used in FCM,ICC/IF,IHC,WB.
SynonymsVitamin D-binding protein, VDB, Group-specific component, Gc-globulin, Gc, DBP
Ig Type
IgG
Clone
2T657
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundVitamin D-binding protein (DBP) is a multi-functional serum protein that binds to the plasma membranes of numerous cell types and mediates a variety of cellular functions. The locus of the DBP protein (also known as group-specific component protein or GC) is located at human chromosome 4q13.3. DBP functions in organ-specific transportation of vitamin D and its metabolites to the various target organs of the vitamin D endocrine system. In addition, DBP has immunomodulatory properties and is able to bind to the surface of leukocytes. DBP binds to the plasma membrane through a chondroitin sulfate proteoglycan. DBP serves as a co-chemotactic factor for C5a to enhance the chemotactic activity of C5a. DBP can also bind to globular Actin with high affinity and is involved in the clearance of Actin from the blood. DBP plays an important role in osteoclast differentiation. The diverse cellular functions of DBP require its cell surface binding ability to mediate different biological processes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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