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Metalaxyl

Name: Metalaxyl
Brand: TargetMol
SKU: T20066
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20066Cas No. 57837-19-1

Alias Ridomil MZ 72 WP, Metalaxil, CGA-48988, CGA48988, CGA 48988, Allegiance

Metalaxyl (CGA 48988) is a widely used fungicide that inhibits protein synthesis in fungi, interferes with skeletal development in zebrafish embryos, and can be used to control plant diseases caused by oomycetous fungi.

Metalaxyl

🥰Excellent

Purity: 99.77%

Catalog No. T20066Alias Ridomil MZ 72 WP, Metalaxil, CGA-48988, CGA48988, CGA 48988, AllegianceCas No. 57837-19-1

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$48	-	In Stock
500 mg	$113	-	In Stock
1 g	$166	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.77%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Metalaxyl (CGA 48988) is a widely used fungicide that inhibits protein synthesis in fungi, interferes with skeletal development in zebrafish embryos, and can be used to control plant diseases caused by oomycetous fungi.
Targets&IC50	pathogenic Aspergillus oryzae fungi:0.3 to 3.9 μg/mL (EC50)
In vitro	Metalaxyl showed potent inhibition of pathogenic Aspergillus oryzae fungi isolated from a potato field in Serbia, with EC50 values ranging from 0.3 to 3.9 μg/mL.[1]
In vivo	In albino rats, Metalaxyl treatment induced dose-dependent bradycardia, with sustained bradycardia culminating in cardiac arrest at higher doses (250 and 300 mg/kg). In addition, acetylcholinesterase activity in the brain and heart of rats was not altered by Metalaxyl treatment. [2]
Synonyms	Ridomil MZ 72 WP, Metalaxil, CGA-48988, CGA48988, CGA 48988, Allegiance

Chemical Properties

Molecular Weight	279.33
Formula	C₁₅H₂₁NO₄
Cas No.	57837-19-1
Smiles	O=C(OC)C(N(C(=O)COC)C=1C(=CC=CC1C)C)C
Relative Density.	1.117 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (286.4 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.81 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5800 mL	17.9000 mL	35.7999 mL	178.9997 mL
5 mM	0.7160 mL	3.5800 mL	7.1600 mL	35.7999 mL
10 mM	0.3580 mL	1.7900 mL	3.5800 mL	17.9000 mL
20 mM	0.1790 mL	0.8950 mL	1.7900 mL	8.9500 mL
50 mM	0.0716 mL	0.3580 mL	0.7160 mL	3.5800 mL
100 mM	0.0358 mL	0.1790 mL	0.3580 mL	1.7900 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc