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Carubicin hydrochloride

Name: Carubicin hydrochloride
Brand: TargetMol
SKU: T26953
Price: 142 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Carubicin HCl, Carminomicin I hydrochloride) Copy Product Info

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Synonyms: Carubicin HCl, Carminomicin I hydrochloride

Catalog No. T26953 Copy Product Info

Purity: 95.84%

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Carubicin hydrochloride is a natural anthracycline anticancer antibiotic structurally related to drugs such as doxorubicin. It exerts its anticancer activity by binding to the DNA double helix and inhibiting topoisomerase II activity, thereby disrupting DNA replication and transcription processes. As a potent anticancer agent, carubicin hydrochloride is commonly used as a research model in tumor biology studies involving DNA damage responses, cell cycle arrest, and apoptosis pathways.

Cas No. 52794-97-5

Pack Size	Price	USA Stock	Global Stock
1 mg	$142	-	In Stock
5 mg	$355	-	In Stock
10 mg	$562	-	In Stock
25 mg	$1,170	-	In Stock
50 mg	$1,760	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:95.84%

Appearance:Solid

Color:Red

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Synonyms

Carubicin HCl, Carminomicin I hydrochloride

Chemical Properties

Molecular Weight	549.95
Formula	C₂₆H₂₈ClNO₁₀
Cas No.	52794-97-5
Smiles	O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4O)C[C@](C(C)=O)(O)C1)[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5.Cl
Relative Density.	1.63g/cm3

Storage & Solubility Information

Storage

Keep away from moisture, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (90.92 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8183 mL	9.0917 mL	18.1835 mL	90.9174 mL
5 mM	0.3637 mL	1.8183 mL	3.6367 mL	18.1835 mL
10 mM	0.1818 mL	0.9092 mL	1.8183 mL	9.0917 mL
20 mM	0.0909 mL	0.4546 mL	0.9092 mL	4.5459 mL
50 mM	0.0364 mL	0.1818 mL	0.3637 mL	1.8183 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc