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Ragifilimab
(Synonyms: INCAGN-1876, INCAGN-01876, CM-701) Copy Product Info
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Synonyms: INCAGN-1876, INCAGN-01876, CM-701
Catalog No. T77138 Copy Product Info
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Ragifilimab (INCAGN-1876) is a monoclonal antibody agonist that specifically targets glucocorticoid-induced TNF receptor-related protein (GITR). Ragifilimab binds to and activates GITR on the surface of T cells, thereby activating effector T cells (Teff) and suppressing the immunosuppressive function of regulatory T cells (Treg), thus stimulating the immune system to enhance its antitumor activity. Ragifilimab is indicated for the treatment of advanced or metastatic solid tumors and for research into tumor immunotherapy mechanisms.
Cas No. 2207590-51-8
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $106 | - | In Stock | |
| 5 mg | $297 | - | In Stock | |
| 10 mg | $463 | - | In Stock | |
| 25 mg | $747 | - | In Stock | |
| 50 mg | $987 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Ragifilimab (INCAGN-1876) is a monoclonal antibody agonist that specifically targets glucocorticoid-induced TNF receptor-related protein (GITR). Ragifilimab binds to and activates GITR on the surface of T cells, thereby activating effector T cells (Teff) and suppressing the immunosuppressive function of regulatory T cells (Treg), thus stimulating the immune system to enhance its antitumor activity. Ragifilimab is indicated for the treatment of advanced or metastatic solid tumors and for research into tumor immunotherapy mechanisms. |
| Endotoxin | <1.0 EU/mg |
| Synonyms | INCAGN-1876, INCAGN-01876, CM-701 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF18/GITR/CD357 |
| Molecular Weight | 146.46 kDa |
| Cas No. | 2207590-51-8 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Ragifilimab chemical structure | Ragifilimab molecular weight
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