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Anti-TRAF2 Antibody (6B229) (Synonyms: Tumor necrosis factor type 2 receptor-associated protein 3, TRAP3, TRAF...)

Catalog No. TMAC-04097 Copy Product Info
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Anti-TRAF2 Antibody (6B229) is a Rabbit antibody targeting TRAF2. Anti-TRAF2 Antibody (6B229) can be used in FCM,ICC/IF,IHC,IP,WB.

Anti-TRAF2 Antibody (6B229)

Copy Product Info
🥰Excellent
Catalog No. TMAC-04097
Synonyms Tumor necrosis factor type 2 receptor-associated protein 3, TRAP3, TRAF 2, TNF receptor-associated factor 2, RING-type E3 ubiquitin transferase TRAF2, EC 2.3.2.27, E3 ubiquitin-protein ligase TRAF2

Anti-TRAF2 Antibody (6B229) is a Rabbit antibody targeting TRAF2. Anti-TRAF2 Antibody (6B229) can be used in FCM,ICC/IF,IHC,IP,WB.

Anti-TRAF2 Antibody
(6B229)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TRAF2 Antibody (6B229) is a Rabbit antibody targeting TRAF2. Anti-TRAF2 Antibody (6B229) can be used in FCM,ICC/IF,IHC,IP,WB.
SynonymsTumor necrosis factor type 2 receptor-associated protein 3, TRAP3, TRAF 2, TNF receptor-associated factor 2, RING-type E3 ubiquitin transferase TRAF2, EC 2.3.2.27, E3 ubiquitin-protein ligase TRAF2
Ig Type
IgG
Clone
6B229
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of TRAF2 on Hela cells lysates using anti-TRAF2 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-TRAF2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-TRAF2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-TRAF2 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-TRAF2 antibody. Counter stained with hematoxylin.
6. ICC staining TRAF2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining TRAF2 in PANC-1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining TRAF2 in RH-35 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. Flow cytometric analysis of Hela cells with TRAF2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
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Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundTumor necrosis factor (TNF)-activated cell signaling is mediated primarily through the TNF receptor 1 (TNF-R1) and, to a lesser extent, TNF-R2. Both TNF receptors are members of the expanding TNF receptor superfamily, which includes the FAS antigen and CD40. Potential insight into an understanding of TNF receptor-mediated signaling was provided by the identification of two related proteins, TRAF1 and TRAF2 (for TNF receptor-associated factors 1 and 2, respectively). Both function to form heterodimeric complexes and associate with the cytoplasmic domain of TNF-R2. A third member of this protein family, alternatively designated CD40 bp, CRAF1, LAP1 or TRAF3, has been identified and shown to associate with the cytoplasmic domain of CD40. The similarity between a specific region of TRAF3 with regions of TRAF1 and TRAF2 define a ??TRAF-C?? domain that is necessary and sufficient for CD40 binding and homodimerization.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 56 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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