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Anti-DLG4 Antibody (7Y949)

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Catalog No. TMAH-00350

Anti-DLG4 Antibody (7Y949) is an antibody targeting DLG4. Anti-DLG4 Antibody (7Y949) can be used in ELISA, WB.

Anti-DLG4 Antibody (7Y949)

Anti-DLG4 Antibody (7Y949)

😃Good
Catalog No. TMAH-00350
Anti-DLG4 Antibody (7Y949) is an antibody targeting DLG4. Anti-DLG4 Antibody (7Y949) can be used in ELISA, WB.
Pack SizePriceAvailabilityQuantity
50 μL$208 7-10 days
100 μL$348 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Monoclonal

Application: ELISA, WB

Reactivity: Human, Mouse, Rat
Ig Type
Rabbit IgG
Clone
7Y949
Reactivity
Human, Mouse, Rat
Verified Activity
Western Blot
-Positive WB detected in: Rat Brain whole cell lysate, Mouse Brain whole cell lysate
-All lanes: PSD95 antibody at 1:1000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 81, 86, 81 kDa
-Observed band size: 95 kDa
Application
ELISA, WB
Recommended Dose
WB:1:500-1:5000.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Lipid-anchor; Cytoplasmic side. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Cytoplasm. Cell projection, axon. Cell projection, dendritic spine. Cell projection, dendrite. Cell junction, synapse, presynapse.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundPostsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human PSD95
Antigen Species
Human
Gene ID
1742
Uniprot ID
Biology Area
Neuroscience
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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