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Anti-IKK- gamma Antibody (1A787)

😃Good
Catalog No. TMAC-02130
Alias ZC2HC9, NF-kappa-B essential modulator, NF-kappa-B essential modifier, NF kappa B essential modulator, NF kappa B essential modifier, NEMO_HUMAN, NEMO, IPD2, IP2, IP1, IP, Inhibitor of nuclear factor kappa-B kinase subunit gamma, Inhibitor of nuclear factor kappa B kinase subunit gamma, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, gamma, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma, Incontinentia pigmenti, IMD33, IKKγ, IKK-gamma, IKKgamma, IKKg, IKKG, IKKAP1, IKK γ, IKK g, Ikbkg, IkB kinase-associated protein 1, IkB kinase subunit gamma, IkB kinase gamma subunit, IkB kinase associated protein 1, I-kappa-B kinase subunit gamma, I kappa B kinase gamma, Fip3p, FIP-3, FIP3, FIP 3, AMCBX1

Anti-IKK- gamma Antibody (1A787) is a Rabbit antibody targeting IKK- gamma. Anti-IKK- gamma Antibody (1A787) can be used in WB,IHC,ICC/IF,IP,FCM.

Anti-IKK- gamma Antibody (1A787)

Anti-IKK- gamma Antibody (1A787)

😃Good
Catalog No. TMAC-02130Alias ZC2HC9, NF-kappa-B essential modulator, NF-kappa-B essential modifier, NF kappa B essential modulator, NF kappa B essential modifier, NEMO_HUMAN, NEMO, IPD2, IP2, IP1, IP, Inhibitor of nuclear factor kappa-B kinase subunit gamma, Inhibitor of nuclear factor kappa B kinase subunit gamma, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, gamma, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma, Incontinentia pigmenti, IMD33, IKKγ, IKK-gamma, IKKgamma, IKKg, IKKG, IKKAP1, IKK γ, IKK g, Ikbkg, IkB kinase-associated protein 1, IkB kinase subunit gamma, IkB kinase gamma subunit, IkB kinase associated protein 1, I-kappa-B kinase subunit gamma, I kappa B kinase gamma, Fip3p, FIP-3, FIP3, FIP 3, AMCBX1
Anti-IKK- gamma Antibody (1A787) is a Rabbit antibody targeting IKK- gamma. Anti-IKK- gamma Antibody (1A787) can be used in WB,IHC,ICC/IF,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-IKK- gamma Antibody (1A787) is a Rabbit antibody targeting IKK- gamma. Anti-IKK- gamma Antibody (1A787) can be used in WB,IHC,ICC/IF,IP,FCM.
SynonymsZC2HC9, NF-kappa-B essential modulator, NF-kappa-B essential modifier, NF kappa B essential modulator, NF kappa B essential modifier, NEMO_HUMAN, NEMO, IPD2, IP2, IP1, IP, Inhibitor of nuclear factor kappa-B kinase subunit gamma, Inhibitor of nuclear factor kappa B kinase subunit gamma, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, gamma, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma, Incontinentia pigmenti, IMD33, IKKγ, IKK-gamma, IKKgamma, IKKg, IKKG, IKKAP1, IKK γ, IKK g, Ikbkg, IkB kinase-associated protein 1, IkB kinase subunit gamma, IkB kinase gamma subunit, IkB kinase associated protein 1, I-kappa-B kinase subunit gamma, I kappa B kinase gamma, Fip3p, FIP-3, FIP3, FIP 3, AMCBX1
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of IKK gamma on Hela cell using anti-IKK gamma antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse fallopian tube tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
7. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-IKK gamma antibody. Counter stained with hematoxylin.
8. ICC staining IKK gamma in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. Flow cytometric analysis of Hela cells with IKK gamma antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:20-50; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundRegulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 48 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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