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Anti-IKK- gamma Antibody (1A787) is a Rabbit antibody targeting IKK- gamma. Anti-IKK- gamma Antibody (1A787) can be used in WB,IHC,ICC/IF,IP,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $497 | 7-10 days |
Description | Anti-IKK- gamma Antibody (1A787) is a Rabbit antibody targeting IKK- gamma. Anti-IKK- gamma Antibody (1A787) can be used in WB,IHC,ICC/IF,IP,FCM. |
Synonyms | ZC2HC9, NF-kappa-B essential modulator, NF-kappa-B essential modifier, NF kappa B essential modulator, NF kappa B essential modifier, NEMO_HUMAN, NEMO, IPD2, IP2, IP1, IP, Inhibitor of nuclear factor kappa-B kinase subunit gamma, Inhibitor of nuclear factor kappa B kinase subunit gamma, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, gamma, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma, Incontinentia pigmenti, IMD33, IKKγ, IKK-gamma, IKKgamma, IKKg, IKKG, IKKAP1, IKK γ, IKK g, Ikbkg, IkB kinase-associated protein 1, IkB kinase subunit gamma, IkB kinase gamma subunit, IkB kinase associated protein 1, I-kappa-B kinase subunit gamma, I kappa B kinase gamma, Fip3p, FIP-3, FIP3, FIP 3, AMCBX1 |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western blot analysis of IKK gamma on Hela cell using anti-IKK gamma antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IKK gamma antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-IKK gamma antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-IKK gamma antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse fallopian tube tissue using anti-IKK gamma antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-IKK gamma antibody. Counter stained with hematoxylin. 7. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-IKK gamma antibody. Counter stained with hematoxylin. 8. ICC staining IKK gamma in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 9. Flow cytometric analysis of Hela cells with IKK gamma antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
Application | |
Recommended Dose | WB: 1:500-2000; IHC: 1:20-50; ICC/IF: 1:50-200; FCM: 1:50-100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 48 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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