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Anti-CDC7 Kinase Antibody (5I139)
😃Good
Catalog No. TMAC-00774
Anti-CDC7 Kinase Antibody (5I139) is a Rabbit antibody targeting CDC7 Kinase. Anti-CDC7 Kinase Antibody (5I139) can be used in WB,FCM.
Anti-CDC7 Kinase Antibody (5I139)
Anti-CDC7 Kinase Antibody (5I139)
😃Good
Catalog No. TMAC-00774
Anti-CDC7 Kinase Antibody (5I139) is a Rabbit antibody targeting CDC7 Kinase. Anti-CDC7 Kinase Antibody (5I139) can be used in WB,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CDC7 Kinase Antibody (5I139) is a Rabbit antibody targeting CDC7 Kinase. Anti-CDC7 Kinase Antibody (5I139) can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-5000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The Dbf4/Cdc7 protein kinase is essential for the activation of replication origins during S phase. Cdc7/Dbf4 efficiently phosphorylates several proteins that are required for the initiation of DNA replication, including five of the six minichromosome maintenance (Mcm) proteins and the p180 subunit of DNA polymerase a-primase. This protein complex consists of the catalytic subunit Cdc7 associating with the regulatory and activating subunit Dbf4. The kinase activity of the complex is regulated throughout the cell cycle, mainly by fluctuating levels of Dbf4. Cdc7 is consistently expressed throughout the cell cycle, while the expression of Dbf4 is absent during G1 phase and accumulates during S and G2 phases. The anaphase-promoting complex rapidly degrades Dbf4 at the time of chromosome segregation, and the stability of Dbf4 remains low during pre-Start G1 phase. The coordinated degradation of Dbf4 and the time of chromosome separation is important to ensuring that prereplicative complexes, which assemble after chromosome segregation, do not immediately refire. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Antigen Species | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 64 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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