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Anti-DDX6 Antibody (4N492)

😃Good
Catalog No. TMAH-00339
Alias RCK, Probable ATP-dependent RNA helicase DDX6, Oncogene RCK, HLR2, EC 3.6.4.13, DEAD box protein 6, ATP-dependent RNA helicase p54

Anti-DDX6 Antibody (4N492) is an antibody targeting DDX6. Anti-DDX6 Antibody (4N492) can be used in ELISA, IHC.

Anti-DDX6 Antibody (4N492)

Anti-DDX6 Antibody (4N492)

😃Good
Catalog No. TMAH-00339Alias RCK, Probable ATP-dependent RNA helicase DDX6, Oncogene RCK, HLR2, EC 3.6.4.13, DEAD box protein 6, ATP-dependent RNA helicase p54
Anti-DDX6 Antibody (4N492) is an antibody targeting DDX6. Anti-DDX6 Antibody (4N492) can be used in ELISA, IHC.
Pack SizePriceAvailabilityQuantity
50 μL$207 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, IHC

Reactivity: Human
AliasRCK, Probable ATP-dependent RNA helicase DDX6, Oncogene RCK, HLR2, EC 3.6.4.13, DEAD box protein 6, ATP-dependent RNA helicase p54
Ig Type
Rabbit IgG
Clone
4N492
Reactivity
Human
Verified Activity
IHC image of TMAH-00339 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Application
ELISA, IHC
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCytoplasm, P-body. Cytoplasm. Nucleus.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundEssential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human DDX6
Antigen Species
Human
Gene ID
1656
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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