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Synonyms: UAQTL1, Placenta specific MDR protein, Placenta specific ATP binding cassette transporter, MXR1, MXR, Multi drug resistance efflux transport ATP binding cassette sub family G(WHITE) member 2, MRX, Mitoxantrone resistance associated protein, MGC102821, GOUT1, EST157481, CDw338 antigen, CDw338, CD338, Breast cancer resistance protein, BMDP, BCRP1, ATP-binding cassette sub-family G member 2, ATP binding cassette transporter G2, ATP binding cassette sub family G(WHITE) member 2, ABCP, ABCG 2, ABC15
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
| Description | Anti-ABCG2 Antibody (4D379) is a Rabbit antibody targeting ABCG2. Anti-ABCG2 Antibody (4D379) can be used in FCM,ICC/IF,IHC,WB. |
| Synonyms | UAQTL1, Placenta specific MDR protein, Placenta specific ATP binding cassette transporter, MXR1, MXR, Multi drug resistance efflux transport ATP binding cassette sub family G(WHITE) member 2, MRX, Mitoxantrone resistance associated protein, MGC102821, GOUT1, EST157481, CDw338 antigen, CDw338, CD338, Breast cancer resistance protein, BMDP, BCRP1, ATP-binding cassette sub-family G member 2, ATP binding cassette transporter G2, ATP binding cassette sub family G(WHITE) member 2, ABCP, ABCG 2, ABC15 |
| Ig Type | IgG |
| Clone | 4D379 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes through the energy of ATP hydrolysis. The ABC half-transporter, ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker. ABCG2 may have N-linked glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 72 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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