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Anti-C Antibody (3X679) is a Rabbit antibody targeting C. Anti-C Antibody (3X679) can be used in WB,ICC,IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $296 | 7-10 days | |
100 μL | $496 | 7-10 days |
Description | Anti-C Antibody (3X679) is a Rabbit antibody targeting C. Anti-C Antibody (3X679) can be used in WB,ICC,IHC. |
Synonyms | THPH4, THPH3, protein C, inactivator of coagulation factors Va and VIIIa, PROC1, PROC, PC, APC |
Ig Type | IgG |
Reactivity | Human |
Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Protein C antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Protein C antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti-Protein C antibody. Counter stained with hematoxylin. 4. ICC staining Protein C in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining Protein C in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
Application | |
Recommended Dose | WB: 1:500; IHC: 1:50-200; ICC: 1:50-200 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Protein C is a vitamin K-dependent plasma protein that is produced in the liver and made up of two polypeptide chains. It is an important coagulant activated by Thrombin bound to an endothelial surface receptor and it enzymatically cleaves activated forms of Factors V and VIII, dest? inflammatory blood coagulation. Protein C is similar to the prothrombin group of blood coagulation factors in its primary structure. Normal protein C concentration in human plasma is approximately 1-3 ng / ml and the proenzyme concentration is approximately 3 μg / ml. Protein C deficiency is associated with inherited thrombophilia, a rare genetic disorder that predisposes affected individuals to venous thrombosis and habitual abortion. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 52 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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