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Anti-NECTIN2 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting NECTIN2. Anti-NECTIN2 Monoclonal Antibody-Biotin can be used in ELISA,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μg | $196 | 12 days | 12 days | |
| 50 μg | $236 | 12 days | 12 days | |
| 100 μg | $330 | 12 days | 12 days |
| Description | Anti-NECTIN2 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting NECTIN2. Anti-NECTIN2 Monoclonal Antibody-Biotin can be used in ELISA,FCM. |
| Synonyms | Poliovirus receptor-related protein 2, Nectin-2, Nectin cell adhesion molecule 2, Herpes virus entry mediator B |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of NECTIN2 overexpressed 439F cells with TMAZ-0230B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of NECTIN2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed: 26755705). Probable cell adhesion protein (PubMed: 9657005)|(Microbial infection) Acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV) |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | NECTIN2 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Other Functions |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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