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Amikacin hydrate

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Catalog No. T6383Cas No. 1257517-67-1
Alias BAY 41-6551 hydrate

Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic with bacteriostatic activity used in studies of drug-resistant Mycobacterium tuberculosis infections and Gram-negative bacterial infections, and is commonly used in the clinic for urinary tract infections caused by E. coli.

Amikacin hydrate
Other Forms of Amikacin hydrate:

Amikacin hydrate

🥰Excellent
Purity: 99.98%
Catalog No. T6383Alias BAY 41-6551 hydrateCas No. 1257517-67-1
Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic with bacteriostatic activity used in studies of drug-resistant Mycobacterium tuberculosis infections and Gram-negative bacterial infections, and is commonly used in the clinic for urinary tract infections caused by E. coli.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$30In StockIn Stock
50 mg$40In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.98%
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Product Introduction

Bioactivity
Description
Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic with bacteriostatic activity used in studies of drug-resistant Mycobacterium tuberculosis infections and Gram-negative bacterial infections, and is commonly used in the clinic for urinary tract infections caused by E. coli.
In vitro
Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth.
In vivo
In male Fischer 344 rats (40-50-day-old), Amikacin hydrate (320 mg/kg; subcutaneous injection; daily; for 10 days) induces hearing loss in rats[3].
SynonymsBAY 41-6551 hydrate
Chemical Properties
Molecular Weight603.623
FormulaC22H43N5O13.xH2O
Cas No.1257517-67-1
SmilesO([C@H]1[C@H](NC([C@H](CCN)O)=O)C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]1O)[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O.O xH2O
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: < 1 mg/mL (insoluble or slightly soluble)
H2O: 40.00 mg/mL (66.27 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.6567 mL8.2833 mL16.5666 mL82.8332 mL
5 mM0.3313 mL1.6567 mL3.3133 mL16.5666 mL
10 mM0.1657 mL0.8283 mL1.6567 mL8.2833 mL
20 mM0.0828 mL0.4142 mL0.8283 mL4.1417 mL
50 mM0.0331 mL0.1657 mL0.3313 mL1.6567 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
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1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

synthesisribosomalproteinototoxickanamycininfectionsGram-negativeBAY-416651 HydrateBAY 416651 HydrateBAY 41-6551BacterialbacillaryAntimicrobialantibioticAntibacterialaminoglycosidesAmikacin
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