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Anti-RAC1/2/3 Antibody (1M237)

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Catalog No. TMAC-03498

Anti-RAC1/2/3 Antibody (1M237) is a Rabbit antibody targeting RAC1/2/3. Anti-RAC1/2/3 Antibody (1M237) can be used in WB,ICC/IF,IHC.

Anti-RAC1/2/3 Antibody (1M237)

Anti-RAC1/2/3 Antibody (1M237)

😃Good
Catalog No. TMAC-03498
Anti-RAC1/2/3 Antibody (1M237) is a Rabbit antibody targeting RAC1/2/3. Anti-RAC1/2/3 Antibody (1M237) can be used in WB,ICC/IF,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-RAC1/2/3 Antibody (1M237) is a Rabbit antibody targeting RAC1/2/3. Anti-RAC1/2/3 Antibody (1M237) can be used in WB,ICC/IF,IHC.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPlasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages (By similarity). Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Chemical Properties
Molecular WeightTheoretical: 21/24 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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