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Anti-Uteroglobin Antibody (7Q840)

😃Good
Catalog No. TMAC-03693
Alias UP-1, SCGB1A1

Anti-Uteroglobin Antibody (7Q840) is a Rabbit antibody targeting Uteroglobin. Anti-Uteroglobin Antibody (7Q840) can be used in WB,ICC,FCM.

Anti-Uteroglobin Antibody (7Q840)

Anti-Uteroglobin Antibody (7Q840)

😃Good
Catalog No. TMAC-03693Alias UP-1, SCGB1A1
Anti-Uteroglobin Antibody (7Q840) is a Rabbit antibody targeting Uteroglobin. Anti-Uteroglobin Antibody (7Q840) can be used in WB,ICC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Uteroglobin Antibody (7Q840) is a Rabbit antibody targeting Uteroglobin. Anti-Uteroglobin Antibody (7Q840) can be used in WB,ICC,FCM.
SynonymsUP-1, SCGB1A1
Ig Type
IgG
Clone
7Q840
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of SCGB1A1 on mouse lung tissue (1) and A549 cell (2) lysate using anti-SCGB1A1 antibody at 1/500 dilution.
2. ICC staining SCGB1A1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining SCGB1A1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining SCGB1A1 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. Flow cytometric analysis of A549 cells with SCGB1A1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Recommended Dose
WB: 1:500-1000; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundSCGB1A1 also named CC10. Clara cell 10 (CC10) protein, a homologue of rabbit uteroglobin, is a phospholipase A2 inhibitor. CC10 is regulated by AP-1, octamer, and hepatocyte nuclear factor-3 (HNF-3) family transcription factors. CC10 expression changes in relation to the ovarian menstrual cycle, and expression in human endometrium may be stimulated by progesterone, suggesting that CC10 may regulate eicosanoid levels in the human uterus. CC10 is expressed in nonciliated airway epithelial cells in the lung and in urogenital secretions. CC10 is involved in modulating inflammation in airway passages and may play a role in asthma. Overexpression of CC10 in the non-small cell lung cancer cell line A549 was shown to result in the near absence of MMP-2 and MMP-9 matrix metalloproteinases and a reduction in invasiveness, indicating that loss of CC10 may contribute to carcinogenesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 10 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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