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Anti-NACC1 Antibody (6F944)

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Catalog No. TMAC-02744
Alias Nucleus accumbens-associated protein 1, NACC1_HUMAN, Nacc 1, NAC-1, NAC1, FLJ37383, btbd14b, BTB/POZ domain-containing protein 14B, BTB Domain Containing 14B, BEND8

Anti-NACC1 Antibody (6F944) is a Mouse antibody targeting NACC1. Anti-NACC1 Antibody (6F944) can be used in WB,IHC.

Anti-NACC1 Antibody (6F944)

Anti-NACC1 Antibody (6F944)

😃Good
Catalog No. TMAC-02744Alias Nucleus accumbens-associated protein 1, NACC1_HUMAN, Nacc 1, NAC-1, NAC1, FLJ37383, btbd14b, BTB/POZ domain-containing protein 14B, BTB Domain Containing 14B, BEND8
Anti-NACC1 Antibody (6F944) is a Mouse antibody targeting NACC1. Anti-NACC1 Antibody (6F944) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4287-10 days
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Product Introduction

Bioactivity
Description
Anti-NACC1 Antibody (6F944) is a Mouse antibody targeting NACC1. Anti-NACC1 Antibody (6F944) can be used in WB,IHC.
SynonymsNucleus accumbens-associated protein 1, NACC1_HUMAN, Nacc 1, NAC-1, NAC1, FLJ37383, btbd14b, BTB/POZ domain-containing protein 14B, BTB Domain Containing 14B, BEND8
Clone
6F944
Reactivity
Human
Verified Activity
1. Western blot analysis of NACC1 on HEK293 (1) and NACC1-hIgGFc transfected HEK293 (2) cell lysate using anti-NACC1 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human mammary cancer tissue using anti-NACC1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-NACC1 antibody. Counter stained with hematoxylin.
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
Research BackgroundThe BTB (broad-complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homooligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 58 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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