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Anti-FSCN1 Antibody (7Z181)

😃Good
Catalog No. TMAC-01447
Alias Strongylocentrotus purpuratus, SNL, Singed drosophila homolog like, Singed (Drosophila) like (sea urchin fascin homolog like), Singed, sea urchin, p55, HSN, FSCN 1, FLJ38511, Fascin1, Fascin homolog 1 actin bundling protein, Fascin homolog 1, Fascin actin bundling protein 1, Fascin 1, Fascin, FAN1, FAN 1, 55 kDa actin-bundling protein, 55 kDa actin bundling protein

Anti-FSCN1 Antibody (7Z181) is a Rabbit antibody targeting FSCN1. Anti-FSCN1 Antibody (7Z181) can be used in WB,ICC/IF,IHC,IP,FCM.

Anti-FSCN1 Antibody (7Z181)

Anti-FSCN1 Antibody (7Z181)

😃Good
Catalog No. TMAC-01447Alias Strongylocentrotus purpuratus, SNL, Singed drosophila homolog like, Singed (Drosophila) like (sea urchin fascin homolog like), Singed, sea urchin, p55, HSN, FSCN 1, FLJ38511, Fascin1, Fascin homolog 1 actin bundling protein, Fascin homolog 1, Fascin actin bundling protein 1, Fascin 1, Fascin, FAN1, FAN 1, 55 kDa actin-bundling protein, 55 kDa actin bundling protein
Anti-FSCN1 Antibody (7Z181) is a Rabbit antibody targeting FSCN1. Anti-FSCN1 Antibody (7Z181) can be used in WB,ICC/IF,IHC,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-FSCN1 Antibody (7Z181) is a Rabbit antibody targeting FSCN1. Anti-FSCN1 Antibody (7Z181) can be used in WB,ICC/IF,IHC,IP,FCM.
SynonymsStrongylocentrotus purpuratus, SNL, Singed drosophila homolog like, Singed (Drosophila) like (sea urchin fascin homolog like), Singed, sea urchin, p55, HSN, FSCN 1, FLJ38511, Fascin1, Fascin homolog 1 actin bundling protein, Fascin homolog 1, Fascin actin bundling protein 1, Fascin 1, Fascin, FAN1, FAN 1, 55 kDa actin-bundling protein, 55 kDa actin bundling protein
Ig Type
IgG
Clone
7Z181
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of Fascin on different lysates using anti-Fascin antibody at 1/1,000 dilution. Positive control: Lane1: SH-SY5Y, Lane2: Human brain, Lane3: Rat spleen, Lane4: Mouse testes, Lane5: Mouse brain, Lane6: Mouse spleen.
2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Fascin antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Fascin antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Fascin antibody. Counter stained with hematoxylin.
5. ICC staining Fascin in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining Fascin in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining Fascin in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. Flow cytometric analysis of Hela cells with Fascin antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCell adhesion to extracellular matrix is an important physiological stimulus for organization of the Actin-based cytoskeleton. Adhesion to the matrix glycoprotein Thrombospondin 1 triggers the sustained formation of F-Actin microspikes that contain the Actin-bundling protein Fascin. These structures are also implicated in cell migration, which may be an important function of Thrombospondin 1 in tissue remodelling and wound repair. Fascin bundles Actin microfilaments within dynamic cellular structures such as microspikes, stress fibers and membrane ruffles. Fascin could serve as a prognostic factor for abnormal ovarian epithelial pathology and could be a novel target for the treatment of ovarian cancer. Fascin, an Actin-bundling protein, identifies dendritic cells in the blood and in tissues.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 54 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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