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G923-0271
🥰Excellent
Catalog No. T120307Cas No. 959554-92-8
G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43 at the cellular level, making it useful for studying diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
G923-0271
🥰Excellent
Catalog No. T120307Cas No. 959554-92-8
G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43 at the cellular level, making it useful for studying diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
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Product Introduction
Bioactivity
Chemical Properties
| Description | G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43 at the cellular level, making it useful for studying diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). |
| Molecular Weight | 450.51 |
| Formula | C28H23FN4O |
| Cas No. | 959554-92-8 |
| Smiles | O=C(NCC1=CC=C(C=C1)C)C2=CC(=NC3=NNC(C=4C=CC(F)=CC4)=C32)C=5C=CC(=CC5)C |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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