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Anti-Twist Antibody (5E952) (Synonyms: TWST1, Twist-related protein 1, Twist1, TWIST homolog of drosophila, ...)

Catalog No. TMAC-04169 Copy Product Info
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Anti-Twist Antibody (5E952) is a Mouse antibody targeting Twist. Anti-Twist Antibody (5E952) can be used in FCM,IF,IP,WB.

Anti-Twist Antibody (5E952)

Copy Product Info
🥰Excellent
Catalog No. TMAC-04169
Synonyms TWST1, Twist-related protein 1, Twist1, TWIST homolog of drosophila, Twist homolog 1(Drosophila), Twist homolog 1, Twist basic helix loop helix transcription factor 1, SCS, OTTHUMP00000116043, H-twist, CRS1, Class A basic helix-loop-helix protein 38, BPES3, BPES2, bHLHa38, B-HLH DNA binding protein, ACS3

Anti-Twist Antibody (5E952) is a Mouse antibody targeting Twist. Anti-Twist Antibody (5E952) can be used in FCM,IF,IP,WB.

Anti-Twist Antibody
(5E952)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Twist Antibody (5E952) is a Mouse antibody targeting Twist. Anti-Twist Antibody (5E952) can be used in FCM,IF,IP,WB.
SynonymsTWST1, Twist-related protein 1, Twist1, TWIST homolog of drosophila, Twist homolog 1(Drosophila), Twist homolog 1, Twist basic helix loop helix transcription factor 1, SCS, OTTHUMP00000116043, H-twist, CRS1, Class A basic helix-loop-helix protein 38, BPES3, BPES2, bHLHa38, B-HLH DNA binding protein, ACS3
Clone
5E952
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of twist expression in non-transfected (A) and human twist transfected (B) 293T whole cell lysates.
verifiedActivity
Application
Recommended Dose
WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate); FCM: 1 μg per 1 x 106 cells
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMembers of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes. Class A proteins include the ubiquitously expressed E-box binding factors E12/E47, ITF2 and HEB (BETA1 or HTF4). Class B proteins such as MyoD, myogenin and NeuroD (BETA2) are transiently expressed and exhibit a much more limited tissue distribution. Class A proteins heterodimerize with class B proteins to activate DNA transcription. Working in opposition to these positively acting factors are a specialized group of proteins that function as dominant negative regulators. Muscle tissue is derived from a subset of cells originating from the embryonic mesoderm. The novel basic helix-loop-helix (bHLH) transcription factor twist is a putative regulator of mesodermal differentiation and myogenesis. Twist is expressed throughout the epithelial somite but not in the myotome. Twist requires dimerization with the E proteins and inhibits myogenic regulatory factors. It has been implicated as regulator of the temporal and spatial formation of myotomes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: a region near the C-terminus of twist of human origin
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 28 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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