Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-NEDD8 Antibody (6A250)

😃Good
Catalog No. TMAC-02770

Anti-NEDD8 Antibody (6A250) is a Rabbit antibody targeting NEDD8. Anti-NEDD8 Antibody (6A250) can be used in WB,ICC/IF,IHC,IP.

Anti-NEDD8 Antibody (6A250)

Anti-NEDD8 Antibody (6A250)

😃Good
Catalog No. TMAC-02770
Anti-NEDD8 Antibody (6A250) is a Rabbit antibody targeting NEDD8. Anti-NEDD8 Antibody (6A250) can be used in WB,ICC/IF,IHC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4967-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-NEDD8 Antibody (6A250) is a Rabbit antibody targeting NEDD8. Anti-NEDD8 Antibody (6A250) can be used in WB,ICC/IF,IHC,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100; ICC/IF: 1:50-200; IP: 1:50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundNEDD8 is a ubiquitin (Ub)-like molecule that shares 80% homology with ubiquitin, a protein known to modify and target various proteins for proteolytic degradation. NEDD8 and the corresponding yeast homolog Rub1 are activated by the E1 ubiquitin activating enzyme UBA2, which forms isopeptide linkages between thio esters. Similar to the Ub-mediated proteolytic pathway, NEDD8 is covalently coupled to an E3 Ub ligase by the E2 conjugating enzyme, Ubc12. NEDD8 preferentially associates with the CUL-2 protein in the E3 ligase complex CBCVHL, which consists of cullin proteins associating with elongin B/C and the tumor suppressor F-box protein, von Hippel Lindau (VHL). NEDD8 is predominantly localized to the nucleus and is highly expressed in adult heart and skeletal muscle. In vitro studies indicate that NEDD8 tetramers are also able to bind to the 26S Proteasome, and that they assemble into complexes with conserved Ub-like moieties, suggesting that NEDD8 may regulate proteolysis of intracellular proteins similar to other Ub-mediated pathways.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 9 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-NEDD8 Antibody (6A250) | purchase Anti-NEDD8 Antibody (6A250) | Anti-NEDD8 Antibody (6A250) cost | order Anti-NEDD8 Antibody (6A250) | Anti-NEDD8 Antibody (6A250) molecular weight