Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-NEDD8 Antibody (6A250) (Synonyms: Ubiquitin-like protein Nedd8, Neural precursor cell expressed developmen...)
Catalog No. TMAC-02770 Copy Product Info
🥰Excellent
Anti-NEDD8 Antibody (6A250) is a Rabbit antibody targeting NEDD8. Anti-NEDD8 Antibody (6A250) can be used in ICC/IF,IHC,IP,WB.
Anti-NEDD8 Antibody (6A250)
Copy Product Info🥰Excellent
Catalog No. TMAC-02770
Synonyms Ubiquitin-like protein Nedd8, Neural precursor cell expressed developmentally down-regulated protein 8, Neddylin, NEDD8
Anti-NEDD8 Antibody (6A250) is a Rabbit antibody targeting NEDD8. Anti-NEDD8 Antibody (6A250) can be used in ICC/IF,IHC,IP,WB.
Anti-NEDD8 Antibody
(6A250)
(6A250)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-NEDD8 Antibody (6A250) is a Rabbit antibody targeting NEDD8. Anti-NEDD8 Antibody (6A250) can be used in ICC/IF,IHC,IP,WB. |
| Synonyms | Ubiquitin-like protein Nedd8, Neural precursor cell expressed developmentally down-regulated protein 8, Neddylin, NEDD8 |
| Ig Type | IgG |
| Clone | 6A250 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-NEDD8 antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-NEDD8 antibody. Counter stained with hematoxylin. 3. ICC staining NEDD8 in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.    |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-100; ICC/IF: 1:50-200; IP: 1:50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | NEDD8 is a ubiquitin (Ub)-like molecule that shares 80% homology with ubiquitin, a protein known to modify and target various proteins for proteolytic degradation. NEDD8 and the corresponding yeast homolog Rub1 are activated by the E1 ubiquitin activating enzyme UBA2, which forms isopeptide linkages between thio esters. Similar to the Ub-mediated proteolytic pathway, NEDD8 is covalently coupled to an E3 Ub ligase by the E2 conjugating enzyme, Ubc12. NEDD8 preferentially associates with the CUL-2 protein in the E3 ligase complex CBCVHL, which consists of cullin proteins associating with elongin B/C and the tumor suppressor F-box protein, von Hippel Lindau (VHL). NEDD8 is predominantly localized to the nucleus and is highly expressed in adult heart and skeletal muscle. In vitro studies indicate that NEDD8 tetramers are also able to bind to the 26S Proteasome, and that they assemble into complexes with conserved Ub-like moieties, suggesting that NEDD8 may regulate proteolysis of intracellular proteins similar to other Ub-mediated pathways. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 9 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-NEDD8 Antibody (6A250) | purchase Anti-NEDD8 Antibody (6A250) | Anti-NEDD8 Antibody (6A250) cost | order Anti-NEDD8 Antibody (6A250) | Anti-NEDD8 Antibody (6A250) molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.