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Anti-SIN3A Antibody (9Z567)

(Synonyms: Transcriptional corepressor Sin3a, Paired amphipathic helix protein Sin3a, Histone deacetylase complex subunit Sin3a) Copy Product Info
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Synonyms: Transcriptional corepressor Sin3a, Paired amphipathic helix protein Sin3a, Histone deacetylase complex subunit Sin3a

Catalog No. TMAC-02653 Copy Product Info
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Anti-SIN3A Antibody (9Z567) is a Rabbit antibody targeting SIN3A. Anti-SIN3A Antibody (9Z567) can be used in FCM,ICC/IF,IHC,WB.
Anti-SIN3A Antibody
(9Z567)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SIN3A Antibody (9Z567) is a Rabbit antibody targeting SIN3A. Anti-SIN3A Antibody (9Z567) can be used in FCM,ICC/IF,IHC,WB.
SynonymsTranscriptional corepressor Sin3a, Paired amphipathic helix protein Sin3a, Histone deacetylase complex subunit Sin3a
Ig Type
IgG
Clone
9Z567
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundIt is now well established that Myc regulation of cell proliferation and differentiation involves a family of related transcription factors. One such factor, Max, is an obligate heterodimeric partner for Myc and can also form heterodimers with at least four related proteins designated Mad 1, Mxi1 (alternatively designated Mad 2), Mad 3 and Mad 4. Like Mad 1 and Mxi1, association of Mad 3 and Mad 4 with Max results in transcriptional repression. Both Myc and the Mad proteins have short half-lives and their synthesis is tightly regulated, while Max expression is constitutive and relatively stable. Two related mammalian cDNAs have been identified and shown to encode Mad-binding proteins. Both possess sequence homology with the yeast transcription repressor Sin3 including four conserved paired amphipathic helix (PAH) domains. mSin3A and mSin3B specifically interact with the Mad proteins via their second paired amphipathic helix domain (PAH2). It has been suggested that Mad-Max heterodimers repress transcription by tethering mSin3 to DNA as corepressors.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 145 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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