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Anti-GART Antibody (9K216)
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Catalog No. TMAC-01625
Alias Trifunctional purine biosynthetic protein adenosine 3, PUR2_HUMAN, PRGS, Phosphoribosylglycinamide synthetase, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosyl-aminoimidazole synthetase, PGFT, PAIS, MGC47764, Glycinamide ribonucleotide synthetase, GARTF, GART, GARS, GAR transformylase, AIRS, AIR synthase, 5'-phosphoribosylglycinamide transformylase
Anti-GART Antibody (9K216) is a Rabbit antibody targeting GART. Anti-GART Antibody (9K216) can be used in WB,ICC/IF,IHC,IP.
Anti-GART Antibody (9K216)
Anti-GART Antibody (9K216)
😃Good
Catalog No. TMAC-01625Alias Trifunctional purine biosynthetic protein adenosine 3, PUR2_HUMAN, PRGS, Phosphoribosylglycinamide synthetase, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosyl-aminoimidazole synthetase, PGFT, PAIS, MGC47764, Glycinamide ribonucleotide synthetase, GARTF, GART, GARS, GAR transformylase, AIRS, AIR synthase, 5'-phosphoribosylglycinamide transformylase
Anti-GART Antibody (9K216) is a Rabbit antibody targeting GART. Anti-GART Antibody (9K216) can be used in WB,ICC/IF,IHC,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-GART Antibody (9K216) is a Rabbit antibody targeting GART. Anti-GART Antibody (9K216) can be used in WB,ICC/IF,IHC,IP. |
| Synonyms | Trifunctional purine biosynthetic protein adenosine 3, PUR2_HUMAN, PRGS, Phosphoribosylglycinamide synthetase, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosyl-aminoimidazole synthetase, PGFT, PAIS, MGC47764, Glycinamide ribonucleotide synthetase, GARTF, GART, GARS, GAR transformylase, AIRS, AIR synthase, 5'-phosphoribosylglycinamide transformylase |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of GART on different lysates using anti-GART antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: 293T, Lane 3: A431. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-GART antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-GART antibody. Counter stained with hematoxylin. 4. ICC staining GART in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining GART in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining GART in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Purines are critical for energy metabolism, cell signaling and cell reproduction and also function as precursors for coenzymes, energy transfer molecules, regulatory factors and proteins involved in RNA and DNA synthesis. GART (GAR transformylase), also referred to as AIRS, GARS, PAIS, PGFT, PRGS or GARTF, is 1,010 amino acids in length and is a key folate-dependent trifunctional enzyme with phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase and AICAR (phosphoribosylaminoimidazole synthetase) activity required for de novo purine biosynthesis. Cancer cells require considerable amounts of purines to sustain their accelerated growth and GART is, therefore, a target for cancer chemotherapy. GART is highly conserved in vertebrates. Two isoforms of GART are expressed due to alternative splicing events. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 107 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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