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Anti-GART Antibody (9K216) (Synonyms: Trifunctional purine biosynthetic protein adenosine 3, PUR2_HUMAN, PRGS|...)

Catalog No. TMAC-01625 Copy Product Info
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Anti-GART Antibody (9K216) is a Rabbit antibody targeting GART. Anti-GART Antibody (9K216) can be used in ICC/IF,IHC,IP,WB.

Anti-GART Antibody (9K216)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01625
Synonyms Trifunctional purine biosynthetic protein adenosine 3, PUR2_HUMAN, PRGS, Phosphoribosylglycinamide synthetase, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosyl-aminoimidazole synthetase, PGFT, PAIS, MGC47764, Glycinamide ribonucleotide synthetase, GARTF, GART, GARS, GAR transformylase, AIRS, AIR synthase, 5'-phosphoribosylglycinamide transformylase

Anti-GART Antibody (9K216) is a Rabbit antibody targeting GART. Anti-GART Antibody (9K216) can be used in ICC/IF,IHC,IP,WB.

Anti-GART Antibody
(9K216)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GART Antibody (9K216) is a Rabbit antibody targeting GART. Anti-GART Antibody (9K216) can be used in ICC/IF,IHC,IP,WB.
SynonymsTrifunctional purine biosynthetic protein adenosine 3, PUR2_HUMAN, PRGS, Phosphoribosylglycinamide synthetase, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, EC 2.1.2.29, Phosphoribosylglycinamide formyltransferase phosphoribosylglycinamide synthetase phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide formyltransferase, Phosphoribosyl-aminoimidazole synthetase, PGFT, PAIS, MGC47764, Glycinamide ribonucleotide synthetase, GARTF, GART, GARS, GAR transformylase, AIRS, AIR synthase, 5'-phosphoribosylglycinamide transformylase
Ig Type
IgG
Clone
9K216
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of GART on different lysates using anti-GART antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: 293T, Lane 3: A431.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-GART antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-GART antibody. Counter stained with hematoxylin.
4. ICC staining GART in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining GART in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining GART in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPurines are critical for energy metabolism, cell signaling and cell reproduction and also function as precursors for coenzymes, energy transfer molecules, regulatory factors and proteins involved in RNA and DNA synthesis. GART (GAR transformylase), also referred to as AIRS, GARS, PAIS, PGFT, PRGS or GARTF, is 1,010 amino acids in length and is a key folate-dependent trifunctional enzyme with phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase and AICAR (phosphoribosylaminoimidazole synthetase) activity required for de novo purine biosynthesis. Cancer cells require considerable amounts of purines to sustain their accelerated growth and GART is, therefore, a target for cancer chemotherapy. GART is highly conserved in vertebrates. Two isoforms of GART are expressed due to alternative splicing events.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 107 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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