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Synonyms: O-6-methylguanine-DNA-alkyltransferase, MGMT, Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNAmethyltransferase
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-MGMT Antibody (9E151) is an antibody targeting MGMT. Anti-MGMT Antibody (9E151) can be used in ELISA,IHC,WB. |
| Synonyms | O-6-methylguanine-DNA-alkyltransferase, MGMT, Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNAmethyltransferase |
| Ig Type | Rabbit IgG |
| Clone | 9E151 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human MGMT |
| Antigen Species | Human |
| Gene Name | MGMT |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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