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Anti-HTT Antibody (6D662)
😃Good
Catalog No. TMAC-02075
Alias Huntington disease protein, Huntingtin, HD protein, HD IT15
Anti-HTT Antibody (6D662) is a Rabbit antibody targeting HTT. Anti-HTT Antibody (6D662) can be used in FCM,ICC,IHC,WB.
Anti-HTT Antibody (6D662)
Anti-HTT Antibody (6D662)
😃Good
Catalog No. TMAC-02075Alias Huntington disease protein, Huntingtin, HD protein, HD IT15
Anti-HTT Antibody (6D662) is a Rabbit antibody targeting HTT. Anti-HTT Antibody (6D662) can be used in FCM,ICC,IHC,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-HTT Antibody (6D662) is a Rabbit antibody targeting HTT. Anti-HTT Antibody (6D662) can be used in FCM,ICC,IHC,WB. |
| Synonyms | Huntington disease protein, Huntingtin, HD protein, HD IT15 |
| Ig Type | IgG |
| Clone | 6D662 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Huntingtin on A431 cell using anti-Huntingtin antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Huntingtin antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-Huntingtin antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse epididymis tissue using anti-Huntingtin antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Huntingtin antibody. Counter stained with hematoxylin. 6. Flow cytometric analysis of SH-SY-5Y cells with Huntingtin antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:500; IHC: 1:50-200; ICC: 1:50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The huntingtin gene, also called the HTT or HD (Huntington disease) gene, is the IT15 ("interesting transcript 15") gene, which codes for a protein called the huntingtin protein. It is variable in its structure, as the many polymorphisms of the gene can lead to variable numbers of glutamine residues present in the protein. The mass of huntingtin protein is dependent largely on the number of glutamine residues it has, the predicted mass is around 350 kDa. Normal huntingtin is generally accepted to be 3144 amino acids in size. The exact function of this protein is not known, but it plays an important role in nerve cells. Within cells, huntingtin may be involved in signaling, transporting materials, binding proteins and other structures, and protecting against programmed cell death (apoptosis). The huntingtin protein is required for normal development before birth. It is expressed in many tissues in the body, with the highest levels of expression seen in the brain. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 347 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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