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Corrector C4

Name: Corrector C4
Brand: TargetMol
SKU: T31014
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T31014Cas No. 421580-53-2

Alias Corrector C-4, Corrector C 4, Corr-4a, Corr4a, Corr 4a

Corrector C4, a corrector commonly used to study cystic fibrosis mutants, works by alleviating the interaction between CFTR transmembrane domain mutants and protein homeostasis.

Corrector C4

🥰Excellent

Purity: 98.36%

Catalog No. T31014Alias Corrector C-4, Corrector C 4, Corr-4a, Corr4a, Corr 4aCas No. 421580-53-2

Corrector C4, a corrector commonly used to study cystic fibrosis mutants, works by alleviating the interaction between CFTR transmembrane domain mutants and protein homeostasis.

Pack Size	Price	Availability
1 mg	$195	In Stock
5 mg	$483	In Stock
10 mg	$692	In Stock
25 mg	$1,080	In Stock
50 mg	$1,490	In Stock
100 mg	$1,970	In Stock
500 mg	$3,930	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:98.36%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Corrector C4, a corrector commonly used to study cystic fibrosis mutants, works by alleviating the interaction between CFTR transmembrane domain mutants and protein homeostasis.
Synonyms	Corrector C-4, Corrector C 4, Corr-4a, Corr4a, Corr 4a

Chemical Properties

Molecular Weight	456.97
Formula	C₂₁H₁₇ClN₄O₂S₂
Cas No.	421580-53-2
Smiles	CC1=C(C=2N=C(NC3=C(OC)C=CC(Cl)=C3)SC2)SC(NC(=O)C4=CC=CC=C4)=N1
Relative Density.	1.440 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (131.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1883 mL	10.9416 mL	21.8833 mL	109.4164 mL
5 mM	0.4377 mL	2.1883 mL	4.3767 mL	21.8833 mL
10 mM	0.2188 mL	1.0942 mL	2.1883 mL	10.9416 mL
20 mM	0.1094 mL	0.5471 mL	1.0942 mL	5.4708 mL
50 mM	0.0438 mL	0.2188 mL	0.4377 mL	2.1883 mL
100 mM	0.0219 mL	0.1094 mL	0.2188 mL	1.0942 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc