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Anti-EEA1 Antibody (2X782)
(Synonyms: Zinc finger FYVE domain-containing protein 2, ZFYVE2, MSTP105, MST105, Endosome-associated protein p162, EEA1, EEA 1, Early endosome associated protein, Early endosome antigen 1, 162kD, Early endosome antigen 1) Copy Product Info
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Synonyms: Zinc finger FYVE domain-containing protein 2, ZFYVE2, MSTP105, MST105, Endosome-associated protein p162, EEA1, EEA 1, Early endosome associated protein, Early endosome antigen 1, 162kD, Early endosome antigen 1
Catalog No. TMAC-01228 Copy Product Info
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Anti-EEA1 Antibody (2X782) is a Mouse antibody targeting EEA1. Anti-EEA1 Antibody (2X782) can be used in ICC,IHC,WB.
Anti-EEA1 Antibody
(2X782)
(2X782)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $427 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-EEA1 Antibody (2X782) is a Mouse antibody targeting EEA1. Anti-EEA1 Antibody (2X782) can be used in ICC,IHC,WB. |
| Synonyms | Zinc finger FYVE domain-containing protein 2, ZFYVE2, MSTP105, MST105, Endosome-associated protein p162, EEA1, EEA 1, Early endosome associated protein, Early endosome antigen 1, 162kD, Early endosome antigen 1 |
| Clone | 2X782 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:2000-5000; ICC: 1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | EEA1 localizes exclusively to early endosomes?and has an important role in endosomal trafficking. EEA1 binds directly to the phospholipid phosphatidylinositol 3-phosphate?through its C-terminalFYVE domain?and forms a homodimer?through a?coiled coil. EEA1 acts as a tethering molecule that couples vesicle docking with SNAREs such as?N-ethylmaleimide sensitive fusion protein, bringing the endosomes physically closer and ultimately resulting in the fusion and delivery of endosomal cargo. Due to the proteins importance in vesicular trafficking, a number of intracellular bacteria prevent EEA1 recruitment to the vacuole.Mycobacterium tuberculosis?is known to inhibit the recruitment of EEA1 to the phagosomal membrane through CamKII. Legionella pneumophila?also prevents EEA1 recruitment through a currently unknown mechanism.[5] Interestingly, the related pathogen Legionella longbeachae?recruits EEA1 and appears to replicate within a modified early endosome. |
| Conjucates | Unconjugated |
| Immunogen | Peptide |
| Uniprot ID |
| Molecular Weight | Theoretical: 162 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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