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Anti-EEA1 Antibody (2X782) (Synonyms: Zinc finger FYVE domain-containing protein 2, ZFYVE2, MSTP105, MST105||...)

Catalog No. TMAC-01228 Copy Product Info
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Anti-EEA1 Antibody (2X782) is a Mouse antibody targeting EEA1. Anti-EEA1 Antibody (2X782) can be used in ICC,IHC,WB.

Anti-EEA1 Antibody (2X782)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01228
Synonyms Zinc finger FYVE domain-containing protein 2, ZFYVE2, MSTP105, MST105, Endosome-associated protein p162, EEA1, EEA 1, Early endosome associated protein, Early endosome antigen 1, 162kD, Early endosome antigen 1

Anti-EEA1 Antibody (2X782) is a Mouse antibody targeting EEA1. Anti-EEA1 Antibody (2X782) can be used in ICC,IHC,WB.

Anti-EEA1 Antibody
(2X782)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-EEA1 Antibody (2X782) is a Mouse antibody targeting EEA1. Anti-EEA1 Antibody (2X782) can be used in ICC,IHC,WB.
SynonymsZinc finger FYVE domain-containing protein 2, ZFYVE2, MSTP105, MST105, Endosome-associated protein p162, EEA1, EEA 1, Early endosome associated protein, Early endosome antigen 1, 162kD, Early endosome antigen 1
Clone
2X782
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis on 293 cell lysates using anti-EEA1 mouse mAb.
2. ICC staining EEA1 in Hela cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining EEA1 in A431 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:2000-5000; ICC: 1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundEEA1 localizes exclusively to early endosomes?and has an important role in endosomal trafficking. EEA1 binds directly to the phospholipid phosphatidylinositol 3-phosphate?through its C-terminalFYVE domain?and forms a homodimer?through a?coiled coil. EEA1 acts as a tethering molecule that couples vesicle docking with SNAREs such as?N-ethylmaleimide sensitive fusion protein, bringing the endosomes physically closer and ultimately resulting in the fusion and delivery of endosomal cargo. Due to the proteins importance in vesicular trafficking, a number of intracellular bacteria prevent EEA1 recruitment to the vacuole.Mycobacterium tuberculosis?is known to inhibit the recruitment of EEA1 to the phagosomal membrane through CamKII. Legionella pneumophila?also prevents EEA1 recruitment through a currently unknown mechanism.[5] Interestingly, the related pathogen Legionella longbeachae?recruits EEA1 and appears to replicate within a modified early endosome.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Peptide
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 162 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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