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Anti-CTLA-4 Antibody (6N484) (Synonyms: IDDM12, GSE, GRD4, cytotoxic T-lymphocyte-associated protein 4, CTLA...)

Catalog No. TMAY-01712 Copy Product Info
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Anti-CTLA-4 Antibody (6N484) is a Rabbit antibody targeting CTLA-4. Anti-CTLA-4 Antibody (6N484) can be used in ELISA.

Anti-CTLA-4 Antibody (6N484)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01712
Synonyms IDDM12, GSE, GRD4, cytotoxic T-lymphocyte-associated protein 4, CTLA-4, CELIAC3, CD152, CD, ALPS5

Anti-CTLA-4 Antibody (6N484) is a Rabbit antibody targeting CTLA-4. Anti-CTLA-4 Antibody (6N484) can be used in ELISA.

Anti-CTLA-4 Antibody
(6N484)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$927-10 days7-10 days
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CTLA-4 Antibody (6N484) is a Rabbit antibody targeting CTLA-4. Anti-CTLA-4 Antibody (6N484) can be used in ELISA.
SynonymsIDDM12, GSE, GRD4, cytotoxic T-lymphocyte-associated protein 4, CTLA-4, CELIAC3, CD152, CD, ALPS5
Ig Type
Rabbit IgG
Clone
6N484
Reactivity
Human
Specificity
Human CTLA-4
Has cross-reactivity in ELISA with
Cynomolgus CTLA4
No cross-reactivity in ELISA with
Mouse CTLA4
Human CD28
Human ICOS
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CTLA-4 / CD152 (rh CTLA-4 / CD152; TMPY-04348; NP_005205.2; Met1-Phe162).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7-1) and CD86 (B7-2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role in their functions. CD152 or cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential receptor involved in the negative regulation of T cell activation. Because of its profound inhibitory role, CD152 has been considered a sound susceptible candidate in autoimmunity and a persuasive target for cancer immunotherapy. In particular, recent evidence suggests that CD152 is also important in the homeostasis and function of a population of suppressive cells, termed regulatory T cells (Treg).Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsCTLA4 / CD152 Immune Checkpoint ProteinsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CTLA-4 / CD152 protein (TMPY-04348)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules, Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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