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Synonyms: type I cytoskeletal 18, KRT18, Keratin-18 (K18), Keratin, type I cytoskeletal 18, Cytokeratin-18 (CK-18), CYK18, Cell proliferation-inducing gene 46 protein
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
| Description | Anti-KRT18 Antibody (5J111) is a Rabbit antibody targeting KRT18. Anti-KRT18 Antibody (5J111) can be used in FCM,ICC/IF,IHC,WB. |
| Synonyms | type I cytoskeletal 18, KRT18, Keratin-18 (K18), Keratin, type I cytoskeletal 18, Cytokeratin-18 (CK-18), CYK18, Cell proliferation-inducing gene 46 protein |
| Ig Type | IgG |
| Clone | 5J111 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:10000-50000; IHC: 1:50-200; ICC/IF: 1:100-500; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. For example, Cytokeratins 10 and 13 are expressed highly in a subset of squamous cell carcinomas while Cytokeratin 18 is expressed in a majority of adenocarcinomas and basal cell carcinomas. Cytokeratin 18 contains two major phosphorylation sites on Ser 33 and Ser 52. Phosphorylation of Ser 18 is essential for the association of Cytokeratin 18 with 14-3-3 proteins and is involved in keratin organization and distribution. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 48 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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