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Anti-CAV2 Antibody (8Z468) is a Mouse antibody targeting CAV2. Anti-CAV2 Antibody (8Z468) can be used in WB,IHC,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $298 | 7-10 days | |
100 μL | $426 | 7-10 days |
Description | Anti-CAV2 Antibody (8Z468) is a Mouse antibody targeting CAV2. Anti-CAV2 Antibody (8Z468) can be used in WB,IHC,FCM. |
Synonyms | OTTHUMP00000195982, OTTHUMP00000025032, MGC12294, Caveolin-2, Caveolin 2 isoform a and b, Caveolin 2, Caveolae protein 20 kD, CAV2_HUMAN, CAV 2, CAV |
Clone | 8Z468 |
Reactivity | Human |
Verified Activity | 1. Western blot analysis of caveolin-2 on human caveolin-2 recombinant protein using anti- caveolin-2 antibody at 1/1,000 dilution. 2. Western blot analysis of caveolin-2 on HEK293 (1) and caveolin-2-hIgGFc transfected HEK293 (2) cell lysate using anti- caveolin-2 3. Western blot analysis of caveolin-2 on different cell lysate using anti- caveolin-2 antibody at 1/1,000 dilution. Positive control: Line1: A549, Line2: 3T3-L1, Line3: A431. 4. Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue using anti- caveolin-2 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissue using anti- caveolin-2 antibody. Counter stained with hematoxylin. 6. Flow cytometric analysis of A549 cells with caveolin-2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
Application | |
Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Caveolae (also known as plasmalemmal vesicles) are 50-100 nM flask-shaped membranes that represent a subcompartment of the plasma membrane. On the basis of morphological studies, caveolae have been implicated to function in the transcytosis of various macromolecules (including LDL) across capillary endothelial cells, uptake of small molecules via potocytosis and the compartmentalization of certain signaling molecules including G protein-coupled receptors. Three proteins, caveolin-1, caveolin-2 and caveolin-3, have been identified as principal components of caveolae (6-8). Two forms of caveolin-1, designated alpha and beta, share a distinct but overlapping cellular distribution and differ by an amino terminal 31 amino acid sequence which is absent from the beta isoform. Caveolin-1 shares 31% identity with caveolin-2 and 65% identity with caveolin-3 at the amino acid level. Functionally, the three proteins differ in their interactions with heterotrimeric G protein isoforms (6-8) |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 18 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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