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Anti-Ube2N Antibody (8H957) (Synonyms: Yeast UBC13 homolog, Ubiquitin-protein ligase N, Ubiquitin-conjugating ...)

Catalog No. TMAC-04187 Copy Product Info
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Anti-Ube2N Antibody (8H957) is a Rabbit antibody targeting Ube2N. Anti-Ube2N Antibody (8H957) can be used in WB.

Anti-Ube2N Antibody (8H957)

Copy Product Info
🥰Excellent
Catalog No. TMAC-04187
Synonyms Yeast UBC13 homolog, Ubiquitin-protein ligase N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin protein ligase N, Ubiquitin conjugating enzyme E2N (UBC13 homolog yeast), Ubiquitin conjugating enzyme E2N (homologous to yeast UBC13), Ubiquitin conjugating enzyme E2N, Ubiquitin conjugating enzyme E2 N, Ubiquitin carrier protein N, UBE2N_HUMAN, Ube2n, Ube 2N, UbcH-ben, UBCHBEN, UbcH13, UbCH ben, Ubc13, UBC 13, MGC8489, MGC131857, Human epidermoid carcinoma mRNA for ubiquitin-conjugating enzyme E2 similar to Drosophila bendless gene product complete cds, HEL-S-71, Epididymis secretory protein Li 71, EC 6.3.2.19, BLU, Bendless-like ubiquitin-conjugating enzyme, Bendless like ubiquitin conjugating enzyme

Anti-Ube2N Antibody (8H957) is a Rabbit antibody targeting Ube2N. Anti-Ube2N Antibody (8H957) can be used in WB.

Anti-Ube2N Antibody
(8H957)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Ube2N Antibody (8H957) is a Rabbit antibody targeting Ube2N. Anti-Ube2N Antibody (8H957) can be used in WB.
SynonymsYeast UBC13 homolog, Ubiquitin-protein ligase N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin protein ligase N, Ubiquitin conjugating enzyme E2N (UBC13 homolog yeast), Ubiquitin conjugating enzyme E2N (homologous to yeast UBC13), Ubiquitin conjugating enzyme E2N, Ubiquitin conjugating enzyme E2 N, Ubiquitin carrier protein N, UBE2N_HUMAN, Ube2n, Ube 2N, UbcH-ben, UBCHBEN, UbcH13, UbCH ben, Ubc13, UBC 13, MGC8489, MGC131857, Human epidermoid carcinoma mRNA for ubiquitin-conjugating enzyme E2 similar to Drosophila bendless gene product complete cds, HEL-S-71, Epididymis secretory protein Li 71, EC 6.3.2.19, BLU, Bendless-like ubiquitin-conjugating enzyme, Bendless like ubiquitin conjugating enzyme
Ig Type
IgG
Clone
8H957
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of Ube2N on different lysates using anti-Ube2N antibody at 1/1,000 dilution. Positive control: Lane 1: Daudi, Lane 2: SH-SY-5Y, Lane 3: Mouse spleen, Lane 4: Rat spleen.
verifiedActivity
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundUbe2N, a member of the E2 Ubiquitin-conjugating enzyme family, completes the second step of ubiquitination reactions, essentially targeting proteins for proteasomic degradation. When proteins are modified with ubiquitin in an important cellular mechanism targeting abnormal or short lived proteins, ubiquitin, a short protein of 76 amino acids, attaches to a lysine residue resting on the target protein. Multiple cycles of ubiquitination create a polyubiquitin chain that the proteasome recognizes and subsequently triggers the ATP-dependent unfolding of the target protein. This allows protoeolytic degradation of the target protein. These degradation products are highly expressed in heart and skeletal muscles. Ube2N moderates the transcriptional activation of target genes, affects the progress of cell differentiation and aging, and also influences the DNA repair pathway, further adding to the survival of cells after DNA damage.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: human Ube2N aa 1-150
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 17 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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