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Anti-Ube2N Antibody (8H957)
😃Good
Catalog No. TMAC-04187
Alias Yeast UBC13 homolog, Ubiquitin-protein ligase N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin protein ligase N, Ubiquitin conjugating enzyme E2N (UBC13 homolog yeast), Ubiquitin conjugating enzyme E2N (homologous to yeast UBC13), Ubiquitin conjugating enzyme E2N, Ubiquitin conjugating enzyme E2 N, Ubiquitin carrier protein N, UBE2N_HUMAN, Ube2n, Ube 2N, UbcH-ben, UBCHBEN, UbcH13, UbCH ben, Ubc13, UBC 13, MGC8489, MGC131857, Human epidermoid carcinoma mRNA for ubiquitin-conjugating enzyme E2 similar to Drosophila bendless gene product complete cds, HEL-S-71, Epididymis secretory protein Li 71, EC 6.3.2.19, BLU, Bendless-like ubiquitin-conjugating enzyme, Bendless like ubiquitin conjugating enzyme
Anti-Ube2N Antibody (8H957) is a Rabbit antibody targeting Ube2N. Anti-Ube2N Antibody (8H957) can be used in WB.
Anti-Ube2N Antibody (8H957)
Anti-Ube2N Antibody (8H957)
😃Good
Catalog No. TMAC-04187Alias Yeast UBC13 homolog, Ubiquitin-protein ligase N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin protein ligase N, Ubiquitin conjugating enzyme E2N (UBC13 homolog yeast), Ubiquitin conjugating enzyme E2N (homologous to yeast UBC13), Ubiquitin conjugating enzyme E2N, Ubiquitin conjugating enzyme E2 N, Ubiquitin carrier protein N, UBE2N_HUMAN, Ube2n, Ube 2N, UbcH-ben, UBCHBEN, UbcH13, UbCH ben, Ubc13, UBC 13, MGC8489, MGC131857, Human epidermoid carcinoma mRNA for ubiquitin-conjugating enzyme E2 similar to Drosophila bendless gene product complete cds, HEL-S-71, Epididymis secretory protein Li 71, EC 6.3.2.19, BLU, Bendless-like ubiquitin-conjugating enzyme, Bendless like ubiquitin conjugating enzyme
Anti-Ube2N Antibody (8H957) is a Rabbit antibody targeting Ube2N. Anti-Ube2N Antibody (8H957) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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| Description | Anti-Ube2N Antibody (8H957) is a Rabbit antibody targeting Ube2N. Anti-Ube2N Antibody (8H957) can be used in WB. |
| Synonyms | Yeast UBC13 homolog, Ubiquitin-protein ligase N, Ubiquitin-conjugating enzyme E2 N, Ubiquitin protein ligase N, Ubiquitin conjugating enzyme E2N (UBC13 homolog yeast), Ubiquitin conjugating enzyme E2N (homologous to yeast UBC13), Ubiquitin conjugating enzyme E2N, Ubiquitin conjugating enzyme E2 N, Ubiquitin carrier protein N, UBE2N_HUMAN, Ube2n, Ube 2N, UbcH-ben, UBCHBEN, UbcH13, UbCH ben, Ubc13, UBC 13, MGC8489, MGC131857, Human epidermoid carcinoma mRNA for ubiquitin-conjugating enzyme E2 similar to Drosophila bendless gene product complete cds, HEL-S-71, Epididymis secretory protein Li 71, EC 6.3.2.19, BLU, Bendless-like ubiquitin-conjugating enzyme, Bendless like ubiquitin conjugating enzyme |
| Ig Type | IgG |
| Clone | 8H957 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Ube2N on different lysates using anti-Ube2N antibody at 1/1,000 dilution. Positive control: Lane 1: Daudi, Lane 2: SH-SY-5Y, Lane 3: Mouse spleen, Lane 4: Rat spleen. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Ube2N, a member of the E2 Ubiquitin-conjugating enzyme family, completes the second step of ubiquitination reactions, essentially targeting proteins for proteasomic degradation. When proteins are modified with ubiquitin in an important cellular mechanism targeting abnormal or short lived proteins, ubiquitin, a short protein of 76 amino acids, attaches to a lysine residue resting on the target protein. Multiple cycles of ubiquitination create a polyubiquitin chain that the proteasome recognizes and subsequently triggers the ATP-dependent unfolding of the target protein. This allows protoeolytic degradation of the target protein. These degradation products are highly expressed in heart and skeletal muscles. Ube2N moderates the transcriptional activation of target genes, affects the progress of cell differentiation and aging, and also influences the DNA repair pathway, further adding to the survival of cells after DNA damage. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human Ube2N aa 1-150 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 17 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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